NCT01846845

Brief Summary

The purpose of the study is to evaluate residual limb circulation and skin health associated with the use of a novel prosthetic transfemoral socket system. A conventional prosthesis will be compared to the novel transfemoral socket system.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
8

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2013

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2013

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 1, 2013

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 3, 2013

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2014

Completed
Last Updated

July 1, 2013

Status Verified

June 1, 2013

Enrollment Period

1.5 years

First QC Date

May 1, 2013

Last Update Submit

June 27, 2013

Conditions

Keywords

Amputee

Outcome Measures

Primary Outcomes (1)

  • Laser Doppler flowmetry tissue perfusion values

    Change from baseline in Laser Doppler flowmetry tissue perfusion values at 1 month

    1 month

Secondary Outcomes (6)

  • Laser speckle flowmetry tissue perfusion values

    1 month

  • Hyperspectral Imaging Tissue Oxygen Saturation (StO2%)

    1 month

  • Trans-Epidermal Water Loss values

    1 month

  • Surface electrical capacitance values

    1 month

  • Elasticity (cutometry) values

    1 month

  • +1 more secondary outcomes

Other Outcomes (2)

  • Skin temperature values

    1 month

  • Prosthesis evaluation questionnaire (PEQ)

    1 month

Study Arms (2)

Conventional TF Socket System

ACTIVE COMPARATOR

Conventional Prosthetic Transfemoral Socket System

Device: Conventional Prosthetic Transfemoral Socket System

Novel TF Socket System

EXPERIMENTAL

Novel Prosthetic Transfemoral Socket System

Device: Novel Prosthetic transfemoral socket system

Interventions

Conventional transfemoral may include an ischial containment socket, a pin suspension socket, and/or suction suspension socket

Also known as: Ischial Containment, Pin Transfemoral Socket, Suction Transfemoroal Socket, Above the knee (AK) socket
Conventional TF Socket System

Prosthetic socket that incorporates lower socket trim-lines and transfemoral vacuum suspension

Novel TF Socket System

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Consenting Adult
  • Unilateral transfemoral amputee
  • Currently suing a liner with prosthesis
  • Uses a prosthesis to ambulate
  • Ability to read, write, and understand English
  • Available during regular business hours for appointments

You may not qualify if:

  • Impaired contra lateral leg
  • Ambulates with the aid of an additional assistive device (e.g. walker, cane, etc.)
  • Diagnosis of renal failure
  • Smoker

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

The Ohio State University Davis Heart and Lung Research Institute

Columbus, Ohio, 43210, United States

RECRUITING

The Ohio Willow Wood Company

Mount Sterling, Ohio, 43143, United States

RECRUITING

Study Officials

  • Gayle Gordillo, MD

    Ohio State University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ryan Schroeder

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 1, 2013

First Posted

May 3, 2013

Study Start

March 1, 2013

Primary Completion

September 1, 2014

Study Completion

September 1, 2014

Last Updated

July 1, 2013

Record last verified: 2013-06

Locations