NCT01841866

Brief Summary

Laryngeal mask airway (LMA) is widely used in children.The appropriate time to remove laryngeal mask airway is still inconclusive.Sore throat is one of common complications after general anesthesia. Sometimes postoperative sore throat affects patients' satisfaction and daily activities. It can be correlated with dysphagia and may limit oral intake especially in children.The incidence of postoperative sore throat after laryngeal mask airway insertion varies from 5.8-34% in adult(13) and 17.5% in pediatric.Somehow, almost the studies of postoperative sore throat after laryngeal mask airway removal were done in awake state. Our study object to test that post operative sore throat after LMA removal in deep anesthetized children is lower than awake children.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
456

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2013

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 24, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 29, 2013

Completed
2 days until next milestone

Study Start

First participant enrolled

May 1, 2013

Completed
6.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2019

Completed
Last Updated

July 31, 2019

Status Verified

July 1, 2019

Enrollment Period

6.4 years

First QC Date

April 24, 2013

Last Update Submit

July 30, 2019

Conditions

Keywords

post operative sore throatlaryngeal mask airwaychildren

Outcome Measures

Primary Outcomes (1)

  • Incidence of Postoperative Sorethroat

    Evaluate post operative sorethroat by using Visual analog scale (VAS) (0-10)

    upto 72 hr post operative period

Secondary Outcomes (8)

  • Dysphagia

    upto 72 hr postoperative period

  • Dysphonia

    upto 72 hr postoperative period

  • Adverse event: teeth or mucosal trauma

    upto 72 hr postoperative period

  • laryngospasm

    Intraoperative and PACU period

  • Bronchospasm

    Intraoperative and PACU period

  • +3 more secondary outcomes

Study Arms (2)

deep anesthetic state

ACTIVE COMPARATOR

LMA removal

Other: LMA removal

awake

PLACEBO COMPARATOR

LMA removal

Other: LMA removal

Interventions

awakedeep anesthetic state

Eligibility Criteria

Age6 Years - 12 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • age 6-12 years
  • ASA physical status I-II
  • elective surgery

You may not qualify if:

  • active airway disease
  • risk for aspiration
  • intraperitoneal or airway surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Prince of Songkla University

Hat Yai, Changwat Songkhla, 90110, Thailand

RECRUITING

Study Officials

  • Ngamjit Pattaravit, MD

    Prince of Songkla University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ngamjit Pattaravit, MD.

CONTACT

Kamonwan Limpadapan, MD.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

April 24, 2013

First Posted

April 29, 2013

Study Start

May 1, 2013

Primary Completion

October 1, 2019

Study Completion

October 1, 2019

Last Updated

July 31, 2019

Record last verified: 2019-07

Locations