NCT01833780

Brief Summary

Study hypothesis: Intrapartum polimeraze chain reaction (PCR)of group B streptoccocus (GBS) test is more accurate than Culture of GBS at 35-37 weeks gestation for GBS carriage. The investigators will compare GBS culture and PCR results taken at 35-37 weeks gestation to intrapartum PCR GBS and GBS cultures status. The larger perspective of this trial is to check the possibility of replacing the GBS culture screening program at 35-37 weeks gestation with a more accurate examination (PCR), avoiding the changing GBS carriage status from the time of culture at 35-37 weeks to delivery.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Status
unknown

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Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 8, 2013

Completed
9 days until next milestone

First Posted

Study publicly available on registry

April 17, 2013

Completed
14 days until next milestone

Study Start

First participant enrolled

May 1, 2013

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
Last Updated

April 18, 2013

Status Verified

April 1, 2013

Enrollment Period

7 months

First QC Date

April 8, 2013

Last Update Submit

April 17, 2013

Conditions

Keywords

carriage statusCulturePCR

Outcome Measures

Primary Outcomes (1)

  • Intrapartum GBS carriage staus measured by PCR and culture compared to GBS culture and PCR at 35-37 weeks gestation

    Intrapartum GBS carriage status measured by culture and PCR will be compared to GBS carriage stauts measured by the same tests at 35-37 weeks gestation.

    One year

Study Arms (2)

GBS carriage status

GBS status during labor

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Unknown GBS pregnant women

You may qualify if:

  • Unknown GBS pregnant women at 35-37 weeks

You may not qualify if:

  • Known GBS pregnant women at 35-37 weeks

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Years
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director, High Risk Unit, Department of OB&GYN, The Baruch Padeh Medical Center, Poriya

Study Record Dates

First Submitted

April 8, 2013

First Posted

April 17, 2013

Study Start

May 1, 2013

Primary Completion

December 1, 2013

Last Updated

April 18, 2013

Record last verified: 2013-04