Pulmonary Blood Flow Measurements in CHF Patients

NCT01831713 | Terminated

• 1 other identifier: NIH DOP08
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Historically, transthoracic Doppler echocardiography has been unable to provide interpretable data of blood flow within the lung parenchyma because of air attenuation of Doppler signals. Recently, a transthoracic Doppler system known as the Sonara/tek Transcranial Doppler (TCD) System has been developed that can identify parenchymal pulmonary blood flow (PPBF) signals. The ability to non-invasively collect information regarding the pulmonary aspect of the cardio-pulmonary system may provide valuable information and new insights into the structural and functional characteristics of the lung parenchyma and vasculature in health and disease states.

Conditions

Congestive Heart Failure (CHF)

Outcome Measures

Primary Outcomes (1)

• Diagnose specific patterns of doppler signals in CHF patients

  December 2013

Study Arms (1)

CHF patients and Controls

CHF patients refer to Decompensated patients and Compensated patients

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

CHF patients admitted to the cardiology telemetry unit and to the CCU

You may qualify if:

• Age over 50 years
• Belongs to one of the following categories:
• A. Decompensated CHF: patients with overt pulmonary congestion or pulmonary edema on admission, evident both clinically and by chest x-ray. Patients may be with or without a Swan-Ganz catheter.
• B. Compensated CHF: patients with significant CHF (NYHA II-IV) who are well controlled and without evidence of pulmonary congestion or pulmonary edema on admission.
• C. Non-CHF controls: patients without CHF and without any of the following: pulmonary hypertension, any known pulmonary disease, uncontrolled hypertension.
• Signed Informed Consent

Sponsors & Collaborators

• Echosense Ltd.: lead

Study Sites (1)

NSLIJ Lenox Hill hospital, 100East 77 Street

New York, New York, 10075, United States

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Study Officials

• Jennifer Chen, MD

  Lenox Hill Hospital, 100East 77 Street New York, NY 10075

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 11, 2013
• First Posted: April 15, 2013
• Study Start: September 1, 2012
• Primary Completion: April 1, 2015
• Study Completion: April 1, 2015
• Last Updated: July 15, 2015

Record last verified: 2012-08

Locations

US (1)