Comparison of Three Treatments for Lower Extremity Apophysitis

NCT01826071 | Completed DMC

• 1 other identifier: 2013-15150
• Study Type: interventional
• Target: 129
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to compare three different treatments for these types of lower extremity apophysitis- Osgood-Schlatter syndrome (OSS), Sinding-Larsen and Johansson syndrome (SLJ), or Sever's disease. The investigators hypothesize that adolescents who perform a home exercise program (HEP) consisting of active elongation exercises will have decreased pain and earlier return to sports and activities as compared to those who perform a HEP that consists of static stretching exercises or those who use symptomatic treatment with ice, acetaminophen or NSAIDs and activity modification.

Conditions

Osgood-Schlatter Syndrome (OSS); Sinding-Larson and Johansson Syndrome (SLJ); Sever's Disease; Apophysitis

Keywords

Osgood-Schlatter syndrome (OSS); Sinding-Larsen and Johansson syndrome (SLJ); Sever's disease; apophysitis; growth; knee

Outcome Measures

Primary Outcomes (1)

• Change in pain rating of a 5 point Likert type pain scale

  The Likert-type pain scale is a self-reported pain scale asking participants to rate pain

  8 weeks

Secondary Outcomes (1)

• Missed time from sports/physical activities

  8 weeks

Study Arms (3)

Symptomatic Treatment

NO INTERVENTION

acetaminophen, NSAID, ice and relative rest

Static Stretch

EXPERIMENTAL

Home exercise program with static stretching

Other: Static Stretch

Active Elongation

EXPERIMENTAL

Home exercise program with active elongation exercises

Other: Active Elongation

Interventions

Static Stretch OTHER

Standing Gastrocnemius Stretch Standing Soleus Stretch Seated Gastrocnemius Stretch Seated Soleus Stretch Hamstring Stretch Quadriceps Stretch (Standing) Quadriceps Stretch (Side Lying)

Static Stretch

Active Elongation OTHER

Mini Squat- Double Leg Mini Squat- Single Leg Prone Hip Extension with Knee Flexed 3 Position Straight Leg Raises Quadriceps Myofascial Release Heel Raises (Eccentric Strengthening) Single Leg and Double Leg Gastrocnemius Myofascial Release Calcaneal Glides

Active Elongation

Eligibility Criteria

• Age: 8 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• diagnosis of OSS, SLJ, or Sever's disease
• must have regular access to the Internet

You may not qualify if:

• history of prior treatment for OSS, SLJ, or Sever's disease
• history of previous injury to the affected joint requiring more than 1 week off of sports or activities

Sponsors & Collaborators

• Ann & Robert H Lurie Children's Hospital of Chicago: lead

Study Sites (1)

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60611, United States

Location

Study Officials

• Rebecca L Carl, MD

  Ann & Robert H Lurie Children's Hospital of Chicago

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Pediatrics

Study Record Dates

• First Submitted: March 29, 2013
• First Posted: April 8, 2013
• Study Start: October 1, 2012
• Primary Completion: October 1, 2023
• Study Completion: October 1, 2023
• Last Updated: February 10, 2025

Record last verified: 2025-02

Locations

US (1)