NCT01823588

Brief Summary

A number of strategies have been evaluated to improve the prevention and control of the main cardiovascular (CVD) risk factors. Nursing telephonic and tele-counseling individualized lifestyle educational programs were found to improve blood pressure (BP) control and adherence to healthy lifestyle. This study aims at evaluating for the first time the efficacy of a nurse-led reminder program through email (NRP-e) to improve CVD risk factors among hypertensive adults. Participants will receive usual care and a guideline-based educational program on BP control and healthy lifestyle habits. Subjects in the NRP-e group will also receive weekly email alerts and phone calls from a nurse care manager for 6 months. Emails contain a reminder program on the compliance with a healthy lifestyle based upon current guidelines for CVD prevention. Follow-up visits will be scheduled at 1, 3 and 6 months after enrollment; randomization will be made centrally and blood samples will be evaluated into a single, accredited laboratory.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
203

participants targeted

Target at P50-P75 for not_applicable hypertension

Timeline
Completed

Started Apr 2013

Shorter than P25 for not_applicable hypertension

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 28, 2013

Completed
4 days until next milestone

Study Start

First participant enrolled

April 1, 2013

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 4, 2013

Completed
27 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2013

Completed
Last Updated

July 22, 2015

Status Verified

July 1, 2015

Enrollment Period

1 month

First QC Date

March 28, 2013

Last Update Submit

July 20, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • The main outcome of the study was the mean difference between groups in the average reduction in systolic and diastolic blood pressure between baseline and the end of follow-up

    6 months

Secondary Outcomes (3)

  • Mean difference between groups in the average reduction in LDL cholesterol between baseline and the end of follow-up

    6 months

  • Mean difference between groups in the average reduction in physical activity between baseline and the end of follow-up

    6 months

  • Mean difference between groups in the average reduction in BMI between baseline and the end of follow-up

    6 months

Study Arms (2)

Usual care

NO INTERVENTION

Educational program and usual cardiovascular prevention.

Nurse-led reminder through email

EXPERIMENTAL

In addition to usual care and educational program, the intervention group will also receive email alerts and phone calls from the nurse-care manager (NCM)

Behavioral: Nurse-led reminder through email.

Interventions

Both groups will receive an educational program and usual care. The educational program will consist of 1-hour sessions, during which the NCM emphasize the importance of blood pressure control and correct measurement, give advice for a correct blood pressure self-measurement; report non-pharmacological strategies for a healthy lifestyle, and instruction on how to fill the daily self-assessment form. Educational program and usual cardiovascular prevention. The educational program will consist of 1-hour sessions, during which the NCM emphasize the importance of blood pressure control and correct measurement, give advice for a correct blood pressure self-measurement; report non-pharmacological strategies for a healthy lifestyle, and instruction on how to fill the daily self-assessment form.

Nurse-led reminder through email

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • to be eligible, all subjects had to be hypertensive (on active treatment for hypertension, or systolic blood pressure ≥ 140 mmHg; or
  • diastolic blood pressure ≥ 90 mmHg).
  • speaking and reading Italian,
  • having a active phone number and an email address, and
  • providing a signed informed consent.

You may not qualify if:

  • mental illness;
  • nursing home institutionalization;
  • pregnancy;
  • previous cardiovascular major events, non-modifiable cardiovascular risk-factors (i.e. diabetes).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

ASL02Abruzzo

Chieti, Abruzzo, 66100, Italy

Location

Department of Medicine and Aging Sciences, University of Chieti

Chieti, CH, 66100, Italy

Location

Related Publications (1)

  • Cicolini G, Simonetti V, Comparcini D, Celiberti I, Di Nicola M, Capasso LM, Flacco ME, Bucci M, Mezzetti A, Manzoli L. Efficacy of a nurse-led email reminder program for cardiovascular prevention risk reduction in hypertensive patients: a randomized controlled trial. Int J Nurs Stud. 2014 Jun;51(6):833-43. doi: 10.1016/j.ijnurstu.2013.10.010. Epub 2013 Oct 25.

MeSH Terms

Conditions

HypertensionCardiovascular Diseases

Condition Hierarchy (Ancestors)

Vascular Diseases

Study Officials

  • Giancarlo GC Cicolini, PhD

    ASL 02 Abruzzo - Abruzzo Region - Italy

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Epidemiology and Public Health

Study Record Dates

First Submitted

March 28, 2013

First Posted

April 4, 2013

Study Start

April 1, 2013

Primary Completion

May 1, 2013

Study Completion

May 1, 2013

Last Updated

July 22, 2015

Record last verified: 2015-07

Locations