NCT01817010

Brief Summary

To determine if patients who receive an 8 week, comprehensive, multi-component rehabilitation program (CMC) have better strength and functional performance compared to a control group (CON). The investigators hypothesize that functional performance and strength in the muscles surrounding the hip and the knee will be greater in the multi-component rehabilitation group compared to the control group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
68

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

March 20, 2013

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 22, 2013

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

July 11, 2016

Status Verified

July 1, 2016

Enrollment Period

3.2 years

First QC Date

March 20, 2013

Last Update Submit

July 8, 2016

Conditions

Keywords

Total Hip ArthroplastyMuscle StrengthHip Osteoarthritis

Outcome Measures

Primary Outcomes (1)

  • Stair Climbing Time

    Time to ascend and descend 12 stairs.

    preoperatively and post operatively at 6, 10, 18 and 28 weeks

Secondary Outcomes (2)

  • Functional Performance Tests

    preoperatively and post operatively at 6, 10, 18 and 28 weeks

  • Isometric Muscle Strength

    preoperatively and post operatively at 6, 10, 18 and 28 weeks

Study Arms (2)

Multi-Component Rehabilitation (CMC)

EXPERIMENTAL

The CMC group will receive a multi-component program focused on rehabilitation of the abdominal and core musculature, neuromuscular re-education through therapeutic exercise as well as hip and knee muscle strengthening beginning 2 weeks after THA.

Behavioral: Multi-Component Rehabilitation (CMC)

Control (CON)

ACTIVE COMPARATOR

The CON group will participate in physical therapist recommended activities based on their home rehabilitation and then will complete the same CMC rehabilitation intervention beginning 10 weeks after THA.

Behavioral: Control (CON)

Interventions

Multi-Component Rehabilitation (CMC)
Control (CON)BEHAVIORAL
Control (CON)

Eligibility Criteria

Age50 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • receiving a total hip replacement secondary to MD diagnosed end-state osteoarthritis only
  • cognitive status that allows patients to consistently comprehend and repeat back directions regarding the details of the study.

You may not qualify if:

  • HbA1c levels greater than 7% based on medical records
  • neurological, vascular or cardiac problems that limit function
  • moderate or severe osteoarthritis or other orthopaedic conditions in the non-operated lower extremity
  • lower back pain which interferes with activities of daily living
  • diagnosed disease which affects muscle function (Parkinson's, Fibromyalgia, Multiple Sclerosis)
  • history of vestibular dysfunction
  • body mass index greater than 40
  • alcoholism or drug abuse

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Colorado Denver, Anschutz Medical Campus

Aurora, Colorado, 80045, United States

Location

MeSH Terms

Conditions

Osteoarthritis, Hip

Interventions

MCC protocol

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • Jennifer Stevens-Lapsley, PT,PhD

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2013

First Posted

March 22, 2013

Study Start

September 1, 2012

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

July 11, 2016

Record last verified: 2016-07

Locations