NCT01813942

Brief Summary

In order to perform research smoothly, the process of information extraction is required for translating data in clinical text into available format for analysis and statistic. In medical research, the problem of missing data occurs frequently. It is important to develop the method with better imputation performance in the stability and accuracy. The purposes of this project are to provide the data integration and extraction methods for handling the structured and unstructured data sources in more efficient ways, to provide the validation scheme for facilitating the data reviewing of extracted results produced by information extraction modules, to increase the quality of clinical data by comparing the data from different data sources and correcting data errors and inconsistent, to handle the clinical data with the properties of time series and incompleteness, to increase accuracy of data analysis and increase quality of health care by improving the completeness and correctness of clinical data, to provide flexibility of methods in the platform. In the project, the disease topic is focused on the liver cancer patients' clinical data and we hope the methods in the projects can be extended to handle other diseases by replacing these knowledge models in the future.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2013

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2013

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

March 5, 2013

Completed
14 days until next milestone

First Posted

Study publicly available on registry

March 19, 2013

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

October 28, 2013

Status Verified

October 1, 2013

Enrollment Period

3 years

First QC Date

March 5, 2013

Last Update Submit

October 25, 2013

Conditions

Keywords

clinical narrative reporttime series datamissing value

Outcome Measures

Primary Outcomes (1)

  • The number of patients correctly identified by recurrence predictive model

    The recurrence predictive model is developed using the incomplete data set, this model is used for predicting the recurrent status of patient who received the specific treatment for liver cancer. The number of patients correctly identified by recurrence predictive model is regarded as the primary outcome measure.

    3 years

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with liver cancer

Patients with liver cancer

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan

RECRUITING

MeSH Terms

Conditions

Liver Neoplasms

Condition Hierarchy (Ancestors)

Digestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesLiver Diseases

Study Officials

  • Feipei Lai

    National Taiwan University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 5, 2013

First Posted

March 19, 2013

Study Start

March 1, 2013

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

October 28, 2013

Record last verified: 2013-10

Locations