The Effect of Home-based Velocity Training in Individuals With Total Knee Replacement

NCT01808781 | Completed DMC

• 1 other identifier: 17263
• Study Type: interventional
• Target: 13
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study will be to find out the effect of two different interventions on muscle strength, ability to produce muscle force quickly (power), daily function, and number of steps and physical activity an individual with total knee replacement do daily. The research hypotheses for this study will be as follows:

• For individuals who are at least 6 months post-total knee replacement, home-based high-velocity training exercises will result in significantly greater improvements in muscle strength and power compared to those who receive a walking program only.
• For individuals who are at least 6 months post-total knee replacement, home based high-velocity training exercises will result in significantly greater improvements of daily function(eg. sit to stand, climb a set of stairs)than those who receive a walking program only.
• For individuals who are at least 6 months post-total knee replacement, home based high-velocity training exercises will result in significantly greater improvements in physical activity behavior (eg. number of steps per day)compared to those who receive a walking program only.

Conditions

Total Knee Arthroplasty

Keywords

Power; muscle strength; total knee replacement; physical activity behavior

Outcome Measures

Primary Outcomes (1)

• Muscle Power

  Change in quadriceps muscle power (force versus velocity)

  Baseline and 8 weeks

Secondary Outcomes (1)

• muscle strength

  Baseline and 8 weeks

Other Outcomes (2)

• Functional Performance

  Baseline and 8 weeks

• Physical activity behavior

  Baseline and 8 weeks

Study Arms (2)

Intervention group

EXPERIMENTAL

Home exercise program plus walking program during 8-week period

Other: Exercises plus walking program

Comparison group

ACTIVE COMPARATOR

Walking only program throughout the 8-week period.

Other: Walking only program

Interventions

Exercises plus walking program OTHER

Exercise group Consist of functional exercises such as mini-squats, sit to stand, and exercises with use of thera-bands. For each exercise, participants will be taught to perform the concentric phase forcefully and as fast as they can and return to the initial position slowly and with control. Participants will be asked to perform the exercises 3 times per week as a home exercise program daily throughout the 8-week intervention period. Additionally, they will be asked to wear a pedometer daily throughout the 8-week intervention to monitor steps. A step goal will be provided to gradually increase daily to become "somewhat active" or "active" by the end of the 8-week intervention.

Intervention group

Walking only program OTHER

Participants will be asked to wear a pedometer and instructions for use just as the exercise group. They will also will given a step goal just as the participants in the exercise group and will similarly be asked to record number of steps form their pedometer in a daily log along with the minutes of moderate and vigorous physical activity throughout the 8-week intervention period.

Comparison group

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Men and women who are at least 40 years of age will qualify if they had a primary unilateral total knee replacement (TKR) 6 to 18 months.

You may not qualify if:

• other lower extremity prosthetic implants other than the current TKR
• revision TKR or plan for revision
• diagnosis of severe osteoarthritis in the uninvolved knee or either hip joints
• recent low extremity injury or significant pain that increases during weight bearing or other functional performance
• diagnosis of neurologic deficits
• decreased cognitive status that might affect the ability to follow instructions
• significant cardiovascular and/or pulmonary disease that limits function

Sponsors & Collaborators

• Texas Woman's University: lead
• Texas Physical Therapy Association: collaborator

Study Sites (1)

Texas Woman's University

Dallas, Texas, 75235-7299, United States

Location

Related Publications (1)

• Trudelle-Jackson E, Hines E, Medley A, Thompson M. Exploration of Habitual Walking Behavior and Home-Based Muscle Power Training in Individuals With Total Knee Arthroplasty. J Phys Act Health. 2020 Mar 1;17(3):331-338. doi: 10.1123/jpah.2019-0233.

  PMID: 32023537 DERIVED

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Emerenciana S Hines, PhD

  Texas Woman's University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD Student

Study Record Dates

• First Submitted: March 6, 2013
• First Posted: March 11, 2013
• Study Start: March 1, 2013
• Primary Completion: January 31, 2017
• Study Completion: January 31, 2017
• Last Updated: October 12, 2017

Record last verified: 2017-10

Data Sharing

• IPD Sharing: Will share

Locations

US (1)