NCT01806246

Brief Summary

The aim of the programme is to develop a treatment model for adolescents with Chronic Fatigue Syndrome. The program consists of 4 elements lasting for 12 months, psychoeducation reflecting the current knowledge about the disease, Heart Rate Variability Coherence Biofeedback, pacing and activity planning and some principles of cognitive behaviour therapy. The study is designed as a Single-Case study including 10- 15 participants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
13

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2013

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2013

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

March 1, 2013

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 7, 2013

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
Last Updated

October 23, 2015

Status Verified

October 1, 2015

Enrollment Period

2.6 years

First QC Date

March 1, 2013

Last Update Submit

October 22, 2015

Conditions

Keywords

rehabilitationadolescentheart rate variability biofeedbackpsychoeducation

Outcome Measures

Primary Outcomes (2)

  • fatigue change

    assessed by Fatigue Severity Scale

    baseline and 52 weeks

  • quality of life change

    assessed by Inventory of Life Quality for Children and Adolescents

    baseline and 52 weeks

Secondary Outcomes (4)

  • mood change

    baseline and 52 weeks

  • change in heart rate variability

    baseline and 52 weeks

  • school attendance change

    baseline and 52 weeks

  • general health change

    baseline and 52 weeks

Study Arms (1)

integrative rehabilitation program

EXPERIMENTAL

28 sessions during 12 months with focus on psychoeducation, activity planning, and thoughts and feelings connected to having a serious chronic disease. From week 13 to week 32 a training programme aiming at balancing heart rate variability.

Behavioral: integrative rehabilitation program

Interventions

integrative rehabilitation program

Eligibility Criteria

Age13 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Participants who meet the diagnostic criteria of chronic fatigue syndrome
  • Clinically evaluated, exclude any disease that can explain the chronic fatigue;
  • Diagnosed and evaluated within the health region, Central Norway
  • With written consent form signed by themselves and their parents.

You may not qualify if:

  • serious comorbidity such as anorexia, psychosis
  • serious depression

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept Child and Adolescent Psychiatry, St Olavs Hospital

Trondheim, Norway

Location

MeSH Terms

Conditions

Fatigue Syndrome, Chronic

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesEncephalomyelitisNeuroinflammatory DiseasesNervous System DiseasesNeuromuscular DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Thomas Jozefiak, md phd

    St. Olavs Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 1, 2013

First Posted

March 7, 2013

Study Start

February 1, 2013

Primary Completion

September 1, 2015

Study Completion

September 1, 2015

Last Updated

October 23, 2015

Record last verified: 2015-10

Locations