NCT01801865

Brief Summary

The purpose of the present study is to make medically indicated state of the art/high end magnetic resonance imaging (MRI) exams available to all infants in the Cincinnati Children's Hospital Medical Center (CCHMC) Neonatal Intensive Care Unit (NICU).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
657

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2012

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

July 25, 2012

Completed
7 months until next milestone

First Posted

Study publicly available on registry

March 1, 2013

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2018

Completed
2.7 years until next milestone

Results Posted

Study results publicly available

October 27, 2020

Completed
Last Updated

October 27, 2020

Status Verified

October 1, 2020

Enrollment Period

5.7 years

First QC Date

July 25, 2012

Results QC Date

September 2, 2020

Last Update Submit

October 2, 2020

Conditions

Keywords

NICUMRINeonatal

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Adverse Events as Observed During and After Scanning.

    Any observed physical changes either related or not related to the MRI was recorded during and after scanning.

    Day 1

Secondary Outcomes (1)

  • Each Infant's Baseline Measurement for Weight Will be Recorded to Ensure the Infant is Less Than 6 kg.

    Day 1

Study Arms (1)

MRI for Neonates

EXPERIMENTAL

All participants will receive an MRI in the NICU scanner in the GE OPTIMA 1.5T MRI at CCHMC.

Device: GE OPTIMA MR430s with HDX/GE Electronics

Interventions

Also known as: GE OPTIMA 1.5T MRI
MRI for Neonates

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Any infant admitted to the NICU at CCHMC
  • Have a medical condition for which an MRI exam is indicated, as determined by the attending neonatologist
  • Able to maintain body temperature for at least 90 minutes without the aid of an incubator or radiant warmer int he opinion of the attending neonatologist
  • Parental/LAR permission obtained

You may not qualify if:

  • Infants too large to fit in the customized NICU MRI system comfortably (expected to be infants heavier than 6 kg)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NICU, Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States

Location

Results Point of Contact

Title
Dr. Beth Kline-Fath
Organization
Cincinnati Children's Hospital Medical Center

Study Officials

  • Beth M Kline-Fath, MD

    Children's Hospital Medical Center, Cincinnati

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 25, 2012

First Posted

March 1, 2013

Study Start

April 1, 2012

Primary Completion

December 1, 2017

Study Completion

March 1, 2018

Last Updated

October 27, 2020

Results First Posted

October 27, 2020

Record last verified: 2020-10

Data Sharing

IPD Sharing
Will not share

Locations