NCT01799031

Brief Summary

This randomized clinical trial studies an educational intervention for reducing work disability in breast cancer survivors. Web sites providing symptom management education may be an effective method to help breast cancer survivors reduce work disability after treatment

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable breast-cancer

Timeline
Completed

Started Jul 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 21, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 26, 2013

Completed
2.3 years until next milestone

Study Start

First participant enrolled

July 1, 2015

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2015

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

November 18, 2019

Status Verified

July 1, 2017

Enrollment Period

3 months

First QC Date

February 21, 2013

Last Update Submit

November 14, 2019

Conditions

Outcome Measures

Primary Outcomes (11)

  • Usability of the WISE website as assessed by responses to a 5-point Likert scale

    The primary analysis of the effect of the WISE intervention on work ability will be performed using a Wilcoxon rank sum test.

    3 months

  • Usability of the WISE website as assessed by responses to a 5-point Likert scale

    The primary analysis of the effect of the WISE intervention on work ability will be performed using a Wilcoxon rank sum test.

    6 months

  • Work ability, assessed by the Work Limitations Questionnaire (WLQ)

    Baseline

  • Work ability, assessed by the WLQ

    3 months

  • Work ability, assessed by the WLQ

    6 months

  • Individual factors, including symptoms assessed using the Symptom Bother-Revised scale (SB-R) and MD Anderson Symptom Inventory (MDASI), socio-demographic factors, individual disease factors, and treatment factors

    Baseline

  • Individual factors, including symptoms assessed using the SB-R and MDASI, socio-demographic factors, individual disease factors, and treatment factors

    3 months

  • Individual factors, including symptoms assessed using the SB-R and MDASI, socio-demographic factors, individual disease factors, and treatment factors

    6 months

  • Workplace factors, including work history, job characteristics, job control, job support, and level of job stress using the Job Content Questionnaire (JCQ)

    Baseline

  • Workplace factors, including work history, job characteristics, job control, job support, and level of job stress using the JCQ

    3 months

  • Workplace factors, including work history, job characteristics, job control, job support, and level of job stress using the JCQ

    6 months

Secondary Outcomes (5)

  • Feasibility measures, including participation/dropout rates, patient satisfaction, usability/satisfaction with WISE, knowledge/use of self-care symptom management/ergonomic strategies, and use of ergonomic/symptom management strategies, and barriers

    Up to 6 months

  • Self-car symptom management strategies used (if any), workplace strategies implemented, and barriers to implementation

    Up to 6 months

  • Individuals self-reported work ability, using the Work Ability Index (WAI)

    Up to 6 months

  • Employment status

    Up to 6 months

  • Change in job performance or difficulty performing work tasks

    Baseline to 6 months

Study Arms (2)

Arm I (WISE)

EXPERIMENTAL

Patients receive access to the WISE web-based educational intervention to help BCS manage their symptoms, identify ergonomic workplace problems and risks, and implement ergonomic modifications. Patients also receive standard of care comprising symptom management therapies and a pamphlet on employment rights.

Other: internet-based interventionProcedure: management of therapy complicationsOther: educational interventionOther: questionnaire administrationProcedure: quality-of-life assessment

Arm II (control)

ACTIVE COMPARATOR

Patients receive standard of care comprising symptom management therapies and a pamphlet on employment rights.

Procedure: management of therapy complicationsOther: questionnaire administrationProcedure: quality-of-life assessment

Interventions

Receive access to the WISE web-based educational intervention

Arm I (WISE)

Receive standard of care

Also known as: complications of therapy, management of
Arm I (WISE)Arm II (control)

Receive access to the WISE web-based educational intervention

Also known as: intervention, educational
Arm I (WISE)

Ancillary studies

Arm I (WISE)Arm II (control)

Ancillary studies

Also known as: quality of life assessment
Arm I (WISE)Arm II (control)

Eligibility Criteria

Age25 Years - 64 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Diagnosed with breast cancer
  • Employed at time of cancer diagnosis (defined as paid employment \> 20 hours/week)
  • Within six months of completion of active treatment
  • Working during treatment or intending to return to work following active treatment
  • Computer and internet access

You may not qualify if:

  • Patients who do not intend to continue/resume working following treatment
  • Develop distant metastases or progressive disease
  • Prior diagnosis of malignancy at any other site except for in situ carcinomas of the cervix or non-melanomatous skin cancers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin Hospital and Clinics

Madison, Wisconsin, 53792, United States

Location

Related Links

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Early Intervention, EducationalMethods

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Child Health ServicesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesPreventive Health ServicesInvestigative Techniques

Study Officials

  • Mary Sesto

    University of Wisconsin, Madison

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 21, 2013

First Posted

February 26, 2013

Study Start

July 1, 2015

Primary Completion

October 1, 2015

Study Completion

June 1, 2017

Last Updated

November 18, 2019

Record last verified: 2017-07

Locations