NCT01792141

Brief Summary

The use of Indocyanine green diagnostic dye will identify areas of vascular leakage which will provide more effective laser treatment by targeting these specific areas.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2011

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 11, 2013

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 15, 2013

Completed
Last Updated

February 15, 2013

Status Verified

February 1, 2013

Enrollment Period

1.4 years

First QC Date

February 11, 2013

Last Update Submit

February 12, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Primary objective is to assess the effectiveness of FA-ICG guided focal laser therapy for the treatment CSME by means of serial FA-1CGs before and every 3 months after treatment.

    Visual Acuity will be measured by using the Early Treatment Diabetic Retinopathy Study. (ETDRS) Macular volume will be measured by Optical coherence tomography.

    3 months

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with Clinically Significant Macular Edema

You may qualify if:

  • Meets criteria for Clinically Significant Macular Edema
  • Microaneurysms hyperfluorescent

You may not qualify if:

  • Increase intraocular pressure
  • Intraocular inflammation
  • Retinal detachment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Retina Institute of Hawaii

Honolulu, Hawaii, 96815, United States

Location

MeSH Terms

Conditions

Macular Edema

Condition Hierarchy (Ancestors)

Macular DegenerationRetinal DegenerationRetinal DiseasesEye Diseases

Study Officials

  • Michael D Bennett, MD

    Retina Institute of Hawaii

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 11, 2013

First Posted

February 15, 2013

Study Start

January 1, 2011

Primary Completion

June 1, 2012

Study Completion

December 1, 2012

Last Updated

February 15, 2013

Record last verified: 2013-02

Locations