NCT01784276

Brief Summary

Specific Aims Our study objective is to investigate if video peer modeling before the visit, plus immersive virtual reality during a preventive dental visit, reduces dental fear and uncooperative behaviors among children with ASD. SPECIFIC AIM: To pilot and test the feasibility and effectiveness of video peer modeling and immersive virtual reality in reducing dental fear among children with autism undergoing preventive dental visits. Methods: The investigators will enroll eighty (80) subjects aged 7-17 years with a known diagnosis of autism, who had a history of dental fear, per parental report. Study hypotheses: The primary hypotheses of interest are: (i) The mean change in the Venham Anxiety Score (VAS) over the 4 month period in children with ASD who receive the video intervention (Group B) is different from the mean change in the VAS over the 4-month period in children with ASD in the control group. (ii) The mean change in the VAS over the 4-month period in children with ASD who receive the immersive VR intervention (Group C) is different from the mean change in the VAS over the 4-month period in children with ASD in the control group. (iii) The mean change in the VAS over the 4-month period in children with ASD who receive the video intervention plus the immersive VR intervention (Group D) is different from the mean change in the VAS over the 4-month period in children with ASD in the control group. The secondary hypothesis is: (i) The mean change in the Venham Behavior Score over the 4-month period in children with ASD in Group D is different from the mean change in the Venham Behavior Score over the 4-month period in children with ASD in Group B or C.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2010

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2010

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2012

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

January 31, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 5, 2013

Completed
Last Updated

February 5, 2013

Status Verified

February 1, 2013

Enrollment Period

1.9 years

First QC Date

January 31, 2013

Last Update Submit

February 2, 2013

Conditions

Keywords

ChildrenAutism Spectrum DisordersElectronic Screen MediaDental fear

Outcome Measures

Primary Outcomes (1)

  • Anxiety

    Primary outcome: Anxiety: To assess the subject's level of anxiety, we will use the Venham Anxiety Rating Scale which assigns numerical values to the child's observable behaviors. It consists of 5 behaviorally defined categories that range from 0-5, and higher scores indicate greater levels of anxiety.(ref) The treating dentist and RA will use the Venham Scale to indicate their perception of level of anxiety experienced by the participant during the dental procedure.

    6 month

Secondary Outcomes (1)

  • Uncooperative behavior

    6 month

Other Outcomes (1)

  • Pulse rate

    6 months

Study Arms (4)

Control

NO INTERVENTION

Children assigned to Group A (control group) received usual care and therefore had no intervention before or during the return visit.

Video peer modeling

EXPERIMENTAL

Video peer modeling (at home, the child watched a DVD recording of a typically developing child undergoing a dental visit);

Behavioral: Video

Video goggles or portable DVD only

EXPERIMENTAL

Video goggles/DVD (during the dental visit, the child watched their favorite movie using sunglass style video eyewear, or portable DVD player);

Behavioral: Video

Video peer modeling plus video goggles

EXPERIMENTAL

Video peer modeling plus video goggles/DVD. At home, the child watched a DVD recording of a typically developing child undergoing a dental visit; During the dental visit, the child watched their favorite movie using sunglass style video eyewear, or portable DVD player.

Behavioral: Video

Interventions

VideoBEHAVIORAL

Video peer modeling: The video demonstrates various stages of the dental visit experience. Children assigned to intervention Groups B or D reviewed the video at least once, but as many times as possible before the follow up visit. Video goggles: This is a sunglass style video eyewear that contains two computer screens that can be used to watch 2 or 3D movies. Subjects randomized to Group C or D watched a 2D movie during the return visit, using the video goggles. Subjects who refused or were unable to wear the goggles watched the movie using a hand held portable DVD player.

Video goggles or portable DVD onlyVideo peer modelingVideo peer modeling plus video goggles

Eligibility Criteria

Age7 Years - 17 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • subjects aged 7-17 years with a known diagnosis of autism, who had a history of dental fear, per parental report.

You may not qualify if:

  • children with motor handicaps (e.g. cerebral palsy), and sensory, vision and hearing impairments (as these would have limited their ability to utilize intervention materials);
  • children with parents who did not speak English or Spanish; and
  • children who presented to clinic without their legal guardian.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Boston Children'S Hospital

Boston, Massachusetts, 02115, United States

Location

MeSH Terms

Conditions

Autism Spectrum Disorder

Interventions

Videotape Recording

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Tape RecordingAudiovisual AidsEducational TechnologyTechnologyTechnology, Industry, and AgricultureTelevision

Study Officials

  • INYANG ISONG, MD

    Boston Children's Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

January 31, 2013

First Posted

February 5, 2013

Study Start

September 1, 2010

Primary Completion

August 1, 2012

Study Completion

August 1, 2012

Last Updated

February 5, 2013

Record last verified: 2013-02

Locations