NCT01784094

Brief Summary

This study aims to compare the Connective Tissue Motion Measure (CTMM) in low back pain and no-low back pain subjects, evaluate the reliability of the CTMM, and examine the correlation of CTMM with low back pain symptoms, disability, and functional measures. The investigators hypothesize that CTMM will be reduced, on average, in low back pain subjects, that CTMM will be reliable with an intra-class correlation greater than 0.8, and CTMM will negatively correlate with low back pain symptoms, disability and functional measures.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
195

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2013

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
29 days until next milestone

First Submitted

Initial submission to the registry

January 30, 2013

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 5, 2013

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2014

Completed
Last Updated

December 30, 2014

Status Verified

December 1, 2014

Enrollment Period

1.7 years

First QC Date

January 30, 2013

Last Update Submit

December 29, 2014

Conditions

Outcome Measures

Primary Outcomes (4)

  • Connective Tissue Shear Strain Motion

    Baseline

  • Change in Connective Tissue Shear Strain Motion

    Baseline to 1 hour

  • Change in Connective Tissue Shear Strain Motion

    Baseline to one day

  • Change in Connective Tissue Shear Strain Motion

    Baseline to one week

Study Arms (2)

Low back pain subjects

Subjects with chronic or recurrent low back pain

Device: StromaGlide

No low back pain subjects

Subjects who are generally healthy with no low back pain

Device: StromaGlide

Interventions

Low back pain subjectsNo low back pain subjects

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Community sample

You may qualify if:

  • able to stand and walk without assistance
  • able to read and understand English
  • able to understand and sign a consent form
  • history of recurrent or chronic low back pain
  • no history of low back pain or other chronic pain that has limited activities of daily living or work
  • numerical chronic pain index of less than 0.5

You may not qualify if:

  • previous severe back or lower extremity injury or surgery
  • major structural spinal deformity (scoliosis, kyphosis, stenosis)
  • ankylosing spondylitis or rheumatoid arthritis
  • neurological deficit (weakness or sensory loss, decreased deep tendon reflexes suggesting nerve root compression, but not subjective symptoms of nerve root irritation (sciatica))
  • radicular pain
  • neurological or major psychiatric disorder
  • bleeding disorders
  • corticosteroid or anticoagulant medication
  • substance abuse
  • pregnancy
  • active worker's compensation or disability case
  • in litigation for a low back pain problem
  • acute systemic infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stromatec, Inc

Burlington, Vermont, 05401, United States

Location

MeSH Terms

Conditions

Low Back PainMusculoskeletal Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsMuscular DiseasesMusculoskeletal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 30, 2013

First Posted

February 5, 2013

Study Start

January 1, 2013

Primary Completion

October 1, 2014

Study Completion

October 1, 2014

Last Updated

December 30, 2014

Record last verified: 2014-12

Locations