NCT01782794

Brief Summary

The present study is conducted in order to assess the acceptability of Hepatitis B vaccination in French general population before and after reimbursement of the paediatric vaccine InfanrixHexa. Four measurements are planned, first before reimbursement and the others at year 1, 2 and 3 after reimbursement.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,413

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2009

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2012

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

January 24, 2013

Completed
11 days until next milestone

First Posted

Study publicly available on registry

February 4, 2013

Completed
Last Updated

February 4, 2013

Status Verified

January 1, 2013

Enrollment Period

3.1 years

First QC Date

January 24, 2013

Last Update Submit

January 31, 2013

Conditions

Keywords

VaccinationAcceptabilityGeneral populationHepatitis BVaccine coverage

Outcome Measures

Primary Outcomes (1)

  • Proportion of infants receiving Hepatitis B vaccination.

    4 years

Secondary Outcomes (2)

  • Evaluation of the immunization coverage levels by other vaccines.

    4 years

  • Acceptability of vaccinating against Hepatitis B.

    4 Years

Study Arms (2)

Cohort A

Children aged 12-15 months at the time of the study. Measurements of Hepatitis B vaccination cover prior to InfanrixHexa reimbursement was obtained from this cohort.

Other: Data collection

Cohort B

Children aged 24-27 months at the time of the study. Measurements of Hepatitis B vaccination cover prior to InfanrixHexa reimbursement was obtained from this cohort.

Other: Data collection

Interventions

Poll and questionnaire-based methodology completed by face-to-face interviews, with possible additional follow-up offered to households.

Cohort ACohort B

Eligibility Criteria

Age12 Months - 27 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

The study population will consist of parents (with infants) agreeing to take part in a personal interview.

You may qualify if:

  • Infants aged 12 to 15 months or 24 to 27 months inclusive at the time of the study.
  • With a parent or legal representative agreeing to take part in the interview.
  • Residing in metropolitan France.

You may not qualify if:

  • Refusal to take part.
  • Infants having lived in another country in their first two years of life.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Gaudelus J, Vie le Sage F, Dufour V, Lert F, Texier N, Pouriel M, Tehard B, Breart G. Public health impact of Infanrix hexa (DTPa-HBV-IPV/Hib) reimbursement: A study programme in France. Part 1: Evolution of hepatitis B vaccine coverage rates in infants aged less than 27 months, in the general population - the PopCorn study. Rev Epidemiol Sante Publique. 2016 Feb;64(1):23-32. doi: 10.1016/j.respe.2015.11.007. Epub 2015 Dec 31.

MeSH Terms

Conditions

Hepatitis B

Interventions

Data Collection

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsHepadnaviridae InfectionsDNA Virus InfectionsVirus DiseasesHepatitis, Viral, HumanHepatitisLiver DiseasesDigestive System Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Officials

  • GSK Clinical Trials

    GlaxoSmithKline

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 24, 2013

First Posted

February 4, 2013

Study Start

May 1, 2009

Primary Completion

June 1, 2012

Study Completion

June 1, 2012

Last Updated

February 4, 2013

Record last verified: 2013-01