Phase I/II Clinical Study of Forodesine in Japanese Recurrent/Refractory Peripheral T-cell Lymphoma Patients

You may not qualify if:

• Patients who received a chemotherapy agent or a high dose of a systemic adrenocorticosteroid within 21 days prior to initial administration of the study drug.
• Patients who received radiation therapy, phototherapy, or electron beam therapy within 21 days prior to initial administration of the study drug.
• Patients who received another study drug within 28 days prior to initial administration of the study drug.
• Patients who received antibody therapy within 100 days prior to initial administration of the study drug.
• Patients with a history of allogeneic hematopoietic stem cell transplantation. Or patients with a history of autologous hematopoietic stem cell transplantation within 100 days prior to initial administration of the study drug.
• Patients with cerebral metastasis or central nervous system lesion or a past history.
• Patients with active multiple primary cancer. Or patients with a history of a malignant neoplasm other than peripheral T-cell lymphoma within the past 5 years.
• Patients with severe cardiovascular disease.
• Patients with congenital long QT syndrome.
• Patients with QTcF \>0.48 sec.
• Patients positive for HBs antigen, HCV antibody or HIV antibody on immunological investigation. Or patients positive for either HBc antibody or HBs antibody, and showing DNA more than sensitivity in HBV-DNA assay.
• Patients positive for CMV antigen on immunological investigation.
• Patients with infectious disease requiring treatment consisting of intravenous administration of antibacterial agent, fungicide, or antiviral drug.
• Patients with interstitial pneumonia or pulmonary fibrosis, or patients judged to have insufficient pulmonary function.