NCT01770639

Brief Summary

The aim of this study is to investigate the clinical outcomes of surgical correction of foot deformity with the MFB in a larger group of patients with neurological impairment of the foot.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
47

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2013

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

January 16, 2013

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 18, 2013

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2014

Completed
Last Updated

June 25, 2014

Status Verified

June 1, 2014

Enrollment Period

1.3 years

First QC Date

January 16, 2013

Last Update Submit

June 24, 2014

Conditions

Keywords

charcot footcharcot neuroarthropathymidfoot arthrodesismidfoot fusion

Outcome Measures

Primary Outcomes (1)

  • Treatment failure within the first year after surgery

    The occurrence and the date of a secondary surgical intervention for correction of deformity or an amputation within the first year after surgery.

    Date of surgery to 1 year posto-op

Secondary Outcomes (5)

  • Treatment failure within the first two years after surgery

    Date of surgery to 2 years post-op

  • Adverse events related to the treatment or device under investigation

    Date of surgery to 2 years post-op

  • Immobilization and non-weightbearing

    Date of surgery to time of full weightbearing

  • Surgery details

    Date of surgery

  • Foot angles

    Pre-op, post-op, 6w, 12w, 6m, 12m

Study Arms (1)

MFB

Surgical arthrodesis of the midfoot with the Midfoot Fusion Bolt (MFB)

Procedure: MFB

Interventions

MFBPROCEDURE

Surgical arthrodesis of the midfoot with the Midfoot Fusion Bolt (MFB)

MFB

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with neuro-osteoarthropathy of the foot or with other neurological impairment in combination with foot deformity who have previously undergone surgical reconstruction of the midfoot with the Midfoot Fusion Bolt.

You may qualify if:

  • Previous surgical reconstruction of the midfoot with Midfoot Fusion Bolt(s) for one of the following indications:
  • Neuroarthropathy Deformity of the foot with neurological impairment - Signed informed consent according to local regulation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Universitätsklinikum Dresden

Dresden, Germany

Location

Universität Rostock

Rostock, Germany

Location

Klinik für Fuss und Sprunggelenkchirurgie Rummelsberg

Rummelsberg, Germany

Location

Related Publications (1)

  • Richter M, Mittlmeier T, Rammelt S, Agren PH, Hahn S, Eschler A. Intramedullary fixation in severe Charcot osteo-neuroarthropathy with foot deformity results in adequate correction without loss of correction - Results from a multi-centre study. Foot Ankle Surg. 2015 Dec;21(4):269-76. doi: 10.1016/j.fas.2015.02.003. Epub 2015 Mar 9.

MeSH Terms

Conditions

Diabetic Foot

Condition Hierarchy (Ancestors)

Diabetic AngiopathiesVascular DiseasesCardiovascular DiseasesFoot UlcerLeg UlcerSkin UlcerSkin DiseasesSkin and Connective Tissue DiseasesDiabetes ComplicationsDiabetes MellitusEndocrine System DiseasesDiabetic Neuropathies

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 16, 2013

First Posted

January 18, 2013

Study Start

January 1, 2013

Primary Completion

May 1, 2014

Study Completion

May 1, 2014

Last Updated

June 25, 2014

Record last verified: 2014-06

Locations