Does Deficiency in Vitamin D Induced Hypercoagulation or Thrombin Generation
1 other identifier
observational
400
1 country
1
Brief Summary
Working hypothesis and aims: The aim of our study is to investigate whether vitamin D deficiency could cause increased thrombin generation and a hypercoagulable state healthy volunteers. Methods: In total 400 healthy volunteers are planned for inclusion in this trial. After signing an informed consent two blood samples will be obtained from each participant. Expected results: invastigator expect to find that volunteers with vitamin D deficiency will have thrombin generation curve compatible with hypercoagulable state and returning to normal after treatment with vitamin D
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2013
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 4, 2012
CompletedFirst Posted
Study publicly available on registry
January 7, 2013
CompletedStudy Start
First participant enrolled
April 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2013
CompletedNovember 3, 2016
December 1, 2014
2 months
December 4, 2012
November 2, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
the correlation between vitamin D levels and endogenous thrombin potential
one blood test
3 month
Study Arms (1)
healthy voulnters
Interventions
Eligibility Criteria
400 healthy volunteers
You may not qualify if:
- no exc criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
HaEmekMC
Afula, 19101, Israel
MeSH Terms
Conditions
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
mazen elias, MD
Emek Medical Center
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Months
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director of Internal Medicine C
Study Record Dates
First Submitted
December 4, 2012
First Posted
January 7, 2013
Study Start
April 1, 2013
Primary Completion
June 1, 2013
Study Completion
July 1, 2013
Last Updated
November 3, 2016
Record last verified: 2014-12