Determination of the Effects and Costs of Respiratory Muscle Training in Institutionalized Elderly People With Functional Impairment: A Randomized Controlled Trial
Sponsor study identifier
Secondary identifiers
OTHER · University of Valencia Research Ethics Committee
interventional
45
1 country
1
Study Start
January 2013
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
July 2013
Actual (reported)Study Completion
December 2013
Actual (reported)The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the older elderly (\>80 years). Respiratory function can be severely compromised if there is a decrease of respiratory (RM) strength complicated by the presence of comorbidities and physical immobility. In this context, the need for supportive services involves the need for long-term care and consequently the institutionalization. Previous studies have shown that the increase of RM strength has positive healthy effects, such as the increase in functional capacity, the decrease in RM fatigue, the decrease of dyspnoea and the improvement of quality of life, both in healthy people and patients. Therefore, specific RM training may be regarded as a beneficial alternative to improve RM function, and thus prevent physical and clinical deterioration in this frail population. Study hypothesis: The inspiratory muscle training (IMT) would improve respiratory muscle strength and endurance, exercise capacity and quality of life in an elderly population, who are unable to engage in general exercise conditioning.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2013
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 31, 2012
Actual (reported)January 2013
Date type not reportedThis date has not been verified as actual or estimated.
January 3, 2013
Actual (reported)July 2013
Actual (reported)December 2013
Actual (reported)Maximum Inspiratory Pressure (MIP)
MIP is probably the most frequently reported noninvasive estimates of inspiratory muscle strength. Ever since Black and Hyatt (1969) reported this technique it has been widely used in patients, healthy control subjects across all ages, and athletes. Pressure is recorded at the mouth during a quasi-static short (few seconds) maximal inspiration. The manoeuvre is generally performed at Residual Volume (RV). Reference: Am J Respir Crit Care Med. 2002;166:531-535.
The groups were assessed at baseline (time zero) and at the end of the training protocol (week 9).
Maximum Expiratory Pressure (MEP)
MEP is probably the most frequently reported noninvasive estimates of expiratory muscle strength. Ever since Black and Hyatt (1969) reported this technique it has been widely used in patients, healthy control subjects across all ages, and athletes. Pressure is recorded at the mouth during a quasi-static short (few seconds) maximal expiration. The manoeuvre is generally performed at Total Lung Capacity (TLC). Reference: Am J Respir Crit Care Med. 2002;166:531-535.
The groups were assessed at baseline (time zero) and at the end of the training protocol (week 9).
Usual care
Participants will breathe against a load ≥ 50% of their baseline MIP, after which loads will increase according to the participant's tolerance across the remaining training period, using a Borg scale rating of 4 to 6 on perceived exertion as an indicator of adequate training intensity.
Interval-based program consisting of seven cycles of 2-minutes work and 1-minute rest. The sessions will take place 3 times per week over a eight-week period for a total of 24 sessions. All participants were familiarized with the breathing exercises over a two-week familiarization period at the beginning of the protocol. The load will be adjusted at ≥ 50% of baseline MIP.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Grupo Gero Residencias "La Saleta"
Valencia, Valencia, 46015, Spain
Geddes EL, O'Brien K, Reid WD, Brooks D, Crowe J. Inspiratory muscle training in adults with chronic obstructive pulmonary disease: an update of a systematic review. Respir Med. 2008 Dec;102(12):1715-29. doi: 10.1016/j.rmed.2008.07.005. Epub 2008 Aug 15.
Gorzoni ML, Pires SL. [Long-term care elderly residents in general hospitals]. Rev Saude Publica. 2006 Dec;40(6):1124-30. doi: 10.1590/s0034-89102006000700024. Portuguese.
M. Àngels Cebrià i Iranzo, PT, PhD
University of Valencia
M. Ángeles Tortosa Chuliá, PhD
University of Valencia
Celedonia Igual Camacho, PT, PhD
University of Valencia
Laura López Bueno, PT, PhD
University of Valencia
45 participants (actual enrollment reported by the registry).
First Submitted
December 31, 2012
First Posted
January 3, 2013
Study Start
January 2013
Date type not reportedThis date has not been verified as actual or estimated.
Effects of Simultaneous Balance and Resistance Training in Older Adults
Maximal Voluntary Ventilation (MVV)
The groups were assessed at baseline (time zero) and at the end of the training protocol (week 9).
Time performed to walk 10 m distance (10mWT).
The groups were assessed at baseline (time zero) and at the end of the training protocol (week 9).
Maximal heart rate achieved at the end of the incremental arm ergometry test.
The groups were assessed at baseline (time zero) and at the end of the training protocol (week 9).
Health-related quality-of-life (CRQ).
The groups were assessed at baseline (time zero) and at the end of the training protocol (week 9).
Contact the study team to confirm eligibility.
Gosselink R, De Vos J, van den Heuvel SP, Segers J, Decramer M, Kwakkel G. Impact of inspiratory muscle training in patients with COPD: what is the evidence? Eur Respir J. 2011 Feb;37(2):416-25. doi: 10.1183/09031936.00031810.
Rydwik E, Frandin K, Akner G. Physical training in institutionalized elderly people with multiple diagnoses--a controlled pilot study. Arch Gerontol Geriatr. 2005 Jan-Feb;40(1):29-44. doi: 10.1016/j.archger.2004.05.009.
Simoes RP, Castello V, Auad MA, Dionisio J, Mazzonetto M. Prevalence of reduced respiratory muscle strength in institutionalized elderly people. Sao Paulo Med J. 2009 May;127(2):78-83. doi: 10.1590/s1516-31802009000200005.
Watsford M, Murphy A. The effects of respiratory-muscle training on exercise in older women. J Aging Phys Act. 2008 Jul;16(3):245-60. doi: 10.1123/japa.16.3.245.
Primary Completion
July 2013
Actual (reported)Study Completion
December 2013
Actual (reported)Last Updated
March 20, 2014
Record last verified: 2014-03
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