NEAT! Technology to Increase Breaks in Sedentary Behavior in Adults With Diabetes

NCT01754467 | Completed Results

• 1 other identifier: CCDTR01
• Study Type: interventional
• Target: 9
• Locations: 1 country
• Sites: 1

Brief Summary

Sedentary behavior is associated with an increased risk of mortality and many health conditions including type 2 diabetes, obesity, cardiovascular disease, and metabolic syndrome, independent of the time spent in moderate-to-vigorous intensity physical activity (MVPA). Furthermore, independent of total sedentary time and MVPA, Healy et al. observed that individuals who had more breaks in sedentary time had lower 2-h plasma glucose. Recent experimental findings also suggests that breaking up prolonged bouts of sedentary behavior (≥ 20 minutes) with either light or moderate intensity activity for 2 minutes reduces postprandial glucose and insulin responses.10 Replacing sedentary time with light-intensity activity or nonexercise activity thermogenesis (NEAT) may help to reduce the health consequences of sedentary behavior. The purpose of this study is to develop a smartphone application (NEAT!) to encourage sedentary adults with diabetes to increase breaks in prolonged bouts of sedentary behavior objectively measured by an accelerometer. NEAT! will be refined by modifying technology created for the ENGAGED trial (RC1DK087126) and will work in conjunction with a Bluetooth enabled accelerometer that can detect bouts of sedentary behavior. When a sedentary bout (≥ 20 minutes) is detected, the smartphone application will trigger a reminder prompt to the user encouraging him/her to participate in NEAT for at least 2 minutes. Following the development, testing, and refining of the application, a sample of 10 sedentary adults with type 2 diabetes will be recruited to participate in a one month trial to examine the feasibility and acceptability of NEAT!. To our knowledge, this is the first study to design and examine the acceptability of a smartphone application that will target interrupting sedentary behavior with NEAT using objectively measured sedentary time in a diabetic population.

Conditions

Diabetes Mellitus

Outcome Measures

Primary Outcomes (1)

• Acceptability of NEAT!

  How many participants would continue to use or use NEAT! in the future

  1 month

Secondary Outcomes (3)

• Adherence to NEAT!

  1 Month

• Breaks in Sedentary Behavior

  Baseline and 1 month

• Changes in Total Sedentary Time

  Baseline and 1 month

Study Arms (1)

NEAT!

EXPERIMENTAL

Participants will use the NEAT! smartphone application and accelerometer over a 1 month period.

Behavioral: NEAT!

Interventions

NEAT! BEHAVIORAL

Participants will wear the accelerometer and use the NEAT! application during waking hours for 1 month. The NEAT! app will prompt participants to stand up when they have been sitting for a prolonged period.

NEAT!

Eligibility Criteria

• Age: 21 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years of age
• have physician diagnosed type 2 diabetes that is currently being treated by dietary modification, oral agents, or insulin
• currently and plan on having an Android smartphone for the next 2 months
• be willing to wear an accelerometer and use the NEAT! application
• spend the majority of the day sitting.

You may not qualify if:

• unable to ambulate without assistance

Sponsors & Collaborators

• Northwestern University: lead

Study Sites (1)

Northwestern University

Chicago, Illinois, 60611, United States

Location

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Results Point of Contact

• Title: Christine Pellegrini, PhD
• Organization: Northwestern University

c-pellegrini@northwestern.edu

312-503-1395

Study Officials

• Christine Pellegrini, Ph.D.

  Northwestern University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant Professor

Study Record Dates

• First Submitted: December 13, 2012
• First Posted: December 21, 2012
• Study Start: February 1, 2013
• Primary Completion: October 1, 2013
• Study Completion: October 1, 2013
• Last Updated: April 28, 2017
• Results First Posted: April 28, 2017

Record last verified: 2017-04

Locations

US (1)