NCT01752010

Brief Summary

The primary objective of this preliminary study is to compare the Tennant BioModulator with Transcutaneous Electrical Nerve Stimulation (TENS) and Traditional Chinese Acupuncture for the management of chronic pain among injured service members. The secondary objective is to investigate any associative effects or benefits on sleep, Post-Traumatic Stress Disorder (PTSD) symptoms, or depression.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
98

participants targeted

Target at P50-P75 for not_applicable chronic-pain

Timeline
Completed

Started May 2010

Longer than P75 for not_applicable chronic-pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2010

Completed
2.6 years until next milestone

First Submitted

Initial submission to the registry

December 14, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 18, 2012

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2014

Completed
Last Updated

May 19, 2015

Status Verified

May 1, 2015

Enrollment Period

3.9 years

First QC Date

December 14, 2012

Last Update Submit

May 18, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Chronic pain

    Baseline; post-intervention; one-month follow up.

Secondary Outcomes (1)

  • Depression, PTSD symptoms, Sleep.

    Baseline; post-intervention; one-month follow up.

Study Arms (3)

Acupuncture Treatment

ACTIVE COMPARATOR

Traditional Chinese acupuncture.

Other: Traditional Chinese Acupuncture

Tennant™ Biomodulator Treatment

ACTIVE COMPARATOR
Device: Tennant™ Biomodulator Treatment

Transcutaneous electrical nerve stimulation (TENS) Treatment

ACTIVE COMPARATOR
Device: Transcutaneous electrical nerve stimulation (TENS) Treatment

Interventions

Treatment will be performed by an experienced provider, and may include insertion of sterile 32-gage (0.25mm) acupuncture needles on any part of the body that can be needled while the subject is lying prone with their head in a face cradle. The needles are usually retained for 20-30 minutes along various meridian points identified by the practitioner as being "blocked." Needles will be inserted to the depth typically recommended for the particular point of concern; generally 1 to 3cm. There are no constraints on the number of needles used. Acupuncture points are points of lower resistance and higher electrical conductance than the surrounding tissue. Placing the acupuncture needles into points identified as blocked is believed to help restore the flow of energy and stimulates the release of endorphins. The subject's level of pain is assessed on a 0-10 pain scale. Thirty minute acupuncture treatments will be given by the provider once a week for 6 weeks at the pain clinic.

Acupuncture Treatment

An FDA-approved Tennant™ 650 BioModulator will be used to deliver electrical stimulation. The device will be applied directly on top of the subject's area of pain for one minute; power is adjusted until the subject feels a slight tingle. Random variations of pulse amplitude are set from zero to a chosen comfort limit. A feedback mechanism is provided by the constant monitoring of skin impedance. The device is then pressed onto the site of pain and rotated counter-clockwise. After a minute, the device is placed on the opposite side of the pain site and the procedure repeated. The subject's level of pain is assessed on a 0-10 pain scale. At no time is the level of electrical stimulation allowed to cause sustained pain. The subject will receive a weekly 15 minute visit that includes a treatment provided by the pain provider. The provider will teach the subject how to use the machine by themselves and instruct the subject to use the machine twice a day on their own during the study.

Tennant™ Biomodulator Treatment

An FDA-approved Empi™ TENS unit will be used to deliver the transcutaneous electrical nerve stimulation. The low frequency TENS unit will be applied to the subject's area of pain by the use of four integrated self-adhering 5x5 cm electrodes. The electrodes will be positioned at a distance of 3 cm and centered over the area that is most painful. The device rapidly delivers therapeutic electrical currents at various frequencies off and on 150 times a second. The subject's level of pain is assessed on a 0-10 pain scale. At no time is the level of electrical stimulation allowed to cause sustained pain. The subject will receive a weekly 15 minute visit that includes a treatment provided by the pain provider. The provider will teach the subject how to use the machine by themselves and instruct the subject to use the machine twice a day on their own during the study.

Transcutaneous electrical nerve stimulation (TENS) Treatment

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Subjects must be Injured service members between the ages of 18 and 60, inclusive;
  • The pain must have been present for 3 months or greater prior to entry into the study;
  • Subjects must agree to follow the medication regime as directed by the pain clinic provider for the duration of the study;
  • Subjects must be able to speak and read English and understand study procedures

You may not qualify if:

  • Epilepsy
  • Pregnancy, or considering pregnancy within the study time-frame
  • Pacemaker
  • History of cardiac arrhythmias
  • Implantable devices (AICD, pump, etc.)
  • Surgical intervention during the past month for the treatment of low back pain or its underlying etiology
  • Documented history of prescription medication abuse
  • Abuse of illicit drugs within the last 6 months
  • Participation in a clinical trial for an investigational drug and/or agent within 30 days prior to screening

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Brooke Army Medical Center

Fort Sam Houston, Texas, 78234, United States

Location

Related Publications (1)

  • Peacock KS, Stoerkel E, Libretto S, Zhang W, Inman A, Schlicher M, Cowsar JD Jr, Eddie D, Walter J. A randomized trial comparing the Tennant Biomodulator to transcutaneous electrical nerve stimulation and traditional Chinese acupuncture for the treatment of chronic pain in military service members. Mil Med Res. 2019 Dec 2;6(1):37. doi: 10.1186/s40779-019-0227-4.

MeSH Terms

Conditions

Chronic PainDepression

Interventions

Transcutaneous Electric Nerve StimulationTherapeutics

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBehavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyPhysical Therapy ModalitiesRehabilitationAnalgesiaAnesthesia and Analgesia

Study Officials

  • Michael Schlicher, PhD

    Brooke Army Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 14, 2012

First Posted

December 18, 2012

Study Start

May 1, 2010

Primary Completion

April 1, 2014

Study Completion

April 1, 2014

Last Updated

May 19, 2015

Record last verified: 2015-05

Locations