NCT01750710

Completed

Correlation Between Clinical and Electrophysiological Phenot...

University Hospital, Clermont-Ferrand Source

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Other study identifiers

Sponsor study identifier

CHU-0128

Study Type

observational

Actual enrollment (reported)

37

Locations

1 country

Sites

1

Timeline

Study Start

December 2012

Actual (reported)

Primary Completion

April 28, 2016

Actual (reported)

Study Completion

April 28, 2016

Actual (reported)

Brief Summary

This exploratory cross-sectional study proposes, firstly, to objectify in a population of Charcot-Marie-Tooth disease type 1A (CMT 1A)if there is a correlation between the recording of electrical parameters and upper limb muscle strength of the thigh and in a second step, to seek a relationship between the measured parameters.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 37 participants
Study completion date: April 28, 2016
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
November 16, 2012
Actual (reported)
Study Start
December 2012
Actual (reported)
First Posted
December 17, 2012
Actual (reported)
Primary Completion
April 28, 2016
Actual (reported)
Study Completion
April 28, 2016
Actual (reported)

Last Updated: October 9, 2019
Status Verified: October 2019
Last Update Submitted: October 8, 2019

Conditions

Charcot-Marie-Tooth Type 1A Neuropathy

Keywords

Charcot-Marie-Tooth disease type 1A neuropathyIsokineticElectromyographyWalking

Outcome Measures

Primary Outcomes (1)

axonal loss
at day 1

Secondary Outcomes (8)

Muscle strength
at day 1
Functional scores
at day 1
Hand testing
at day 1
spatial and temporal parameters of walking
at day 1
Barometric stabilometric podo-static scores
at day 1
+3 more secondary outcomes

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

Patients suffering from CMT 1A neuropathy

You may qualify if:

Patients older than 18 years

Sponsors & Collaborators

University Hospital, Clermont-Ferrand
Otherlead

Study Sites (1)

CHU Clermont-Ferrand

Clermont-Ferrand, 63003, France

Related Publications (1)

Bihel L, Reynaud V, Givron P, Clavelou P, Cornut-Chauvinc C, Pereira B, Thomas E, Taithe F, Coudeyre E. Foot Function Index: A Promising Questionnaire for Individuals With Charcot-Marie-Tooth Disease Type 1A. Arch Phys Med Rehabil. 2019 Dec;100(12):2403-2406. doi: 10.1016/j.apmr.2019.06.003. Epub 2019 Jun 28.
PMID: 31255638DERIVED

MeSH Terms

Conditions

Charcot-Marie-Tooth Disease

Condition Hierarchy (Ancestors)

Hereditary Sensory and Motor NeuropathyNervous System MalformationsNervous System DiseasesHeredodegenerative Disorders, Nervous SystemNeurodegenerative DiseasesPolyneuropathiesPeripheral Nervous System DiseasesNeuromuscular DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesGenetic Diseases, Inborn

Study Officials

Emmanuel COUDEYRE
University Hospital, Clermont-Ferrand
PRINCIPAL INVESTIGATOR

Enrollment

37 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: OTHER
Time Perspective: CROSS SECTIONAL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

November 16, 2012

First Posted

December 17, 2012

Study Start

December 2012

Actual (reported)

Diagnosis of Charcot Marie Tooth disease, type 1A confirmed by molecular biology (duplication 17.p11.2)

Listening and written French

Agreement after written information, clear and honest about the purpose of the study, the nature of the tests and their possible side effects or bothersome.

Strength of the quadriceps superior to 2/5 MMT MRC

You may not qualify if:

Presence of other neurological comorbidity
Presence of coronary artery disease unstabilized
Peripheral neuropathy of other causes: diabetes, monoclonal gammopathy, malignancy, solid cancer, systemic autoimmune disease (lupus, Sjögren's disease, Wegener sarcoidosis ...), infectious disease (viral hepatitis, HIV ...), drugs known to be responsible for iatrogenic neuropathy.
Gait trouble of other origin
Patients unable to give their consent.
Intellectual deficit that does not allow to comply with tests

Contact the study team to confirm eligibility.

Primary Completion

April 28, 2016

Actual (reported)

Study Completion

April 28, 2016

Actual (reported)

Last Updated

October 9, 2019

Record last verified: 2019-10

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT01750710
Data provider: ClinicalTrials.gov
Source updated: 2019-10-09
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:27:23 UTC

Locations

FR(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

Study Start

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (8)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations