NCT01742650

Brief Summary

The aim of our study is to compare two different syndesmosis transfixation methods in AO/OTA Weber C ankle fractures. Our hypothesis is that 50% of screw fixed fibulas but only 5% of suture-button fixed fibulas are in malposition. All skeletally mature patients (16 years or older) with AO/OTA Weber C type fractures operated within a week after trauma are consecutively included into the study. The tibiofibular transfixation is randomly performed either by a 3,5 mm tricortical screw or a suture-button (TightRope). Malposition of the tibiofibular joint is assessed in an intraoperative computed tomography. Clinical outcome is assessed by using Olerud-Molander, RAND ja 36-Item Healt Survey after 1-year from the injury.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2010

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2010

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

June 12, 2012

Completed
6 months until next milestone

First Posted

Study publicly available on registry

December 5, 2012

Completed
Last Updated

May 16, 2016

Status Verified

May 1, 2016

Enrollment Period

1.4 years

First QC Date

June 12, 2012

Last Update Submit

May 13, 2016

Conditions

Keywords

ankle; fracture; syndesmosis;

Outcome Measures

Primary Outcomes (1)

  • Malreduction of the tibiofibular joint in the intraoperative computed tomography

    Malreduction in the tibiofibular joint is assessed post op from the intraoperative computed tomography. Both ankles are imaged and difference at least 2 mm is assessed to be significant

    2 years

Secondary Outcomes (1)

  • Clinical outcome one year after the injury

    2 year

Study Arms (2)

Screw fixation

ACTIVE COMPARATOR

3,5mm fully threaded cortical screw transfixation of syndesmosis

Procedure: Screw fixation

TightRope

ACTIVE COMPARATOR

TightRope transfixation of syndesmosis

Procedure: TightRope

Interventions

3,5mm fully threaded cortical screw transfixation of syndesmosis

Screw fixation
TightRopePROCEDURE

TightRope transfixation of syndesmosis

Also known as: Tightrope Arthrex
TightRope

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • AO/OTA Weber C ankle fracture, operation within 7 days from the injury

You may not qualify if:

  • Bilateral or previous ankle fracture, tibial shaft fracture, diabetes wiht polyneuropathy, inadequate co-operation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oulu University Hospital

Oulu, 90029, Finland

Location

Related Publications (1)

  • Kortekangas T, Savola O, Flinkkila T, Lepojarvi S, Nortunen S, Ohtonen P, Katisko J, Pakarinen H. A prospective randomised study comparing TightRope and syndesmotic screw fixation for accuracy and maintenance of syndesmotic reduction assessed with bilateral computed tomography. Injury. 2015;46(6):1119-26. doi: 10.1016/j.injury.2015.02.004. Epub 2015 Feb 21.

MeSH Terms

Conditions

Wounds and InjuriesFractures, Bone

Study Officials

  • Tero HJ Kortekangas, MD

    Oulu University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

June 12, 2012

First Posted

December 5, 2012

Study Start

July 1, 2010

Primary Completion

December 1, 2011

Study Completion

December 1, 2011

Last Updated

May 16, 2016

Record last verified: 2016-05

Data Sharing

IPD Sharing
Will not share

Locations