NCT01735331

Brief Summary

The aim of this study is determine vascular endothelial growth factor levels and angiogenesis/vascularity from hysteroscopic endometrial biopsies which taken from patients who has Recurrent Pregnancy Loss.The endometrial vascular endothelial growth factor levels will be measured by immunohistochemical staining methods due to office hysteroscopic endometrial biopsy after the menstruation at follicular phase of menstrual cycle.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2012

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2012

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

November 26, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 28, 2012

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2013

Completed
Last Updated

August 7, 2015

Status Verified

August 1, 2015

Enrollment Period

9 months

First QC Date

November 26, 2012

Last Update Submit

August 6, 2015

Conditions

Recurrent Pregnancy Loss Without Current Pregnancy

Keywords

Vascular endothelial growth factor, Recurrent Pregnancy Loss

Outcome Measures

Primary Outcomes (1)

  • The primary outcome measure of this study is to determine endometrial vascular endothelial growth factor levels in patient with Recurrent Pregnancy Loss

    3 months

Study Arms (2)

VEGF level

VEGF level in hysteroscopic endometrial biopsy of the patients with recurrent pregnancy loss.

control group

Patients with Abnormal Uterine Bleeding

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

The patients with Recurrent Pregnancy Loss

You may qualify if:

  • Patients with Recurrent Pregnancy Loss who accept to join the study.

You may not qualify if:

  • Patients whose age of \<18 and \>45
  • Patients with have any pregnancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bagcilar Training and Research Hospital

Istanbul, Turkey (Türkiye)

Location

Study Officials

  • TANER A. USTA, M.D.

    Bagcilar Training and Research Hospital,Istanbul,Turkey.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 26, 2012

First Posted

November 28, 2012

Study Start

November 1, 2012

Primary Completion

August 1, 2013

Study Completion

August 1, 2013

Last Updated

August 7, 2015

Record last verified: 2015-08

Locations

TU(1)