NCT01733576

Brief Summary

This project will use a new form of non-invasive brain stimulation called high-definition transcranial direct current stimulation (HD-tDCS) to facilitate verbal learning. This form of stimulation is similar to transcranial direct current stimulation (tDCS) but allows for more spatially focused stimulation. We hypothesise that HD-tDCS when applied to regions of the brain important for learning and memory will improve verbal learning and memory compared to sham HD-tDCS.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at P25-P50 for early_phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 26, 2012

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 27, 2012

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2014

Completed
Last Updated

July 23, 2015

Status Verified

July 1, 2015

First QC Date

November 26, 2012

Last Update Submit

July 21, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Ray Auditory Verbal Learning Test (RAVLT)

Study Arms (4)

Sham HD-tDCS

SHAM COMPARATOR
Device: HD-tDCS

Active HD-tDCS 1

ACTIVE COMPARATOR
Device: HD-tDCS

Active HD-tDCS 2

ACTIVE COMPARATOR
Device: HD-tDCS

Active HD-tDCS 3

ACTIVE COMPARATOR
Device: HD-tDCS

Interventions

HD-tDCSDEVICE
Active HD-tDCS 1Active HD-tDCS 2Active HD-tDCS 3Sham HD-tDCS

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Ages 18 - 40 years
  • Right-handed

You may not qualify if:

  • concurrent medication likely to affect mental performance
  • current history of drug or alcohol abuse or dependence
  • any psychiatric or neurological disorder, recent head injury, or history of seizure or stroke.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Black Dog Institute

Sydney, New South Wales, 2031, Australia

Location

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant

Study Record Dates

First Submitted

November 26, 2012

First Posted

November 27, 2012

Primary Completion

March 1, 2014

Last Updated

July 23, 2015

Record last verified: 2015-07

Locations