Intensive Outpatient Services for Teens
INVEST
Intensive Outpatient Protocol for High Risk Suicidal Teens
1 other identifier
interventional
140
1 country
1
Brief Summary
This study will identify the effectiveness of an intensive treatment program for teens who are at high risk for harming themselves.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_1 depression
Started Sep 2012
Longer than P75 for phase_1 depression
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2012
CompletedFirst Submitted
Initial submission to the registry
November 13, 2012
CompletedFirst Posted
Study publicly available on registry
November 26, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2018
CompletedJanuary 23, 2018
January 1, 2018
5.1 years
November 13, 2012
January 21, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Suicide attempts
Self-report by parents or teens of a suicide attempt occurring in the follow-up period
Measured at 18 months from Baseline
Secondary Outcomes (1)
Depressed mood as assessed by the Children's Depression Rating Scale - Revised
Measured at 18 months from Baseline
Other Outcomes (1)
Other self harm behaviors including Nonsuicidal self-injury (NSSI) substance abuse
Measures 18 months from Baseline
Study Arms (2)
Intensive Outpatient CBT
EXPERIMENTALIntensive CBT for both parents and adolescents as well as family sessions to increase communication.
Standard Care
ACTIVE COMPARATORStandard Treatment in the Community
Interventions
Sessions will be delivered 1-2 times a week for the first 4-6 weeks, based on need, and then weekly until 6 months. Therapy can continue up until one year.
Treatment at step-down facilities
Eligibility Criteria
You may qualify if:
- Current Mood Disorder and suicidal ideation and one of the following
- NSSI
- Suicide Attempt
- Substance Use
You may not qualify if:
- Intelligence Quotient \< 80
- Diagnosis of psychotic disorder, pervasive developmental disorder, obsessive-compulsive disorder, bulimia nervosa or anorexia nervosa
- Adolescent use of illicit "hard" substances such as cocaine, heroine, and opiates 13 or more times over the prior 90 days
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Brown Universitylead
- National Institute of Mental Health (NIMH)collaborator
Study Sites (1)
Brown University
Providence, Rhode Island, 02912, United States
Related Publications (1)
Esposito-Smythers C, Wolff JC, Liu RT, Hunt JI, Adams L, Kim K, Frazier EA, Yen S, Dickstein DP, Spirito A. Family-focused cognitive behavioral treatment for depressed adolescents in suicidal crisis with co-occurring risk factors: a randomized trial. J Child Psychol Psychiatry. 2019 Oct;60(10):1133-1141. doi: 10.1111/jcpp.13095. Epub 2019 Jul 21.
PMID: 31328281DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Anthony Spirito, PhD
Brown University
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
November 13, 2012
First Posted
November 26, 2012
Study Start
September 1, 2012
Primary Completion
October 1, 2017
Study Completion
January 1, 2018
Last Updated
January 23, 2018
Record last verified: 2018-01