NCT01731522

Brief Summary

The purpose of this study is to examine the influence of two Eating Frequency prescriptions, meal (energy intake occurring during three meals per day) and grazing (energy intake occurring every two to three hours per day), on consumption during an ad libitum meal consumed at the end of the day, overall daily energy intake, and ratio of energy intake to energy expenditure. It is hypothesized that the grazing condition will produce lower consumption during an evening ad libitum meal, lower daily energy intake, and a lower ratio of energy intake to energy expenditure than the meal condition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 14, 2012

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 21, 2012

Completed
10 days until next milestone

Study Start

First participant enrolled

December 1, 2012

Completed
6.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2018

Completed
7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

June 9, 2026

Status Verified

June 1, 2026

Enrollment Period

6.1 years

First QC Date

November 14, 2012

Last Update Submit

June 5, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Total grams of ad libitum meal consumed

    The foods that will be used in this investigation are Tyson Chicken Breast Tenders, Ore-Ida Tater Tots, Birds Eye Steamfresh Pure \& Simple green beans, and Sarah Lee Butter Pound Cake. Participants will be provided with ad libitum amounts of the foods, and the foods will be measured in grams to the tenth decimal point on an electronic food scale (Denver Instrument Co., Arvada, CO) before and after the meal. The weight of the container will also be measured. Total grams of each food consumed during the session will be determined by subtracting pre- and post-consumption weight of food.

    1 year

Study Arms (1)

EF condition

EXPERIMENTAL
Behavioral: EF condition

Interventions

EF conditionBEHAVIORAL
Also known as: Grazing, Three meal
EF condition

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • age between 18 and 35 years
  • body mass index (BMI) between 18.5 and 24.9 kg/m2
  • no history of overweight or obesity
  • unrestrained eater (\<12 on Three Factor Eating Questionnaire \[TFEQ\])
  • regularly participate in at least 150 minutes of moderate-intense physical activity per week over the previous 4 weeks

You may not qualify if:

  • currently taking medication that affects appetite or food intake
  • have a medical condition affecting eating or currently following a therapeutic diet
  • are currently participating in a weight loss program and/or taking weight loss medication
  • have gained or lost \> 5% of body weight during the past 6 months
  • diagnosed with type 1 or 2 diabetes
  • have had bariatric surgery
  • report disliking foods used in the investigation (scoring a 1 or 2 on a 5-point Likert scale)
  • report having allergies to foods used in the investigation
  • currently smoke
  • report binge eating
  • are graduate students in the Department of Nutrition
  • are pregnant, lactating, \< 6 months post-partum.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Tennessee-Knoxville

Knoxville, Tennessee, 37996-1920, United States

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 14, 2012

First Posted

November 21, 2012

Study Start

December 1, 2012

Primary Completion

December 31, 2018

Study Completion

December 31, 2025

Last Updated

June 9, 2026

Record last verified: 2026-06

Locations