NCT01727284

Enrolling By Invitation

MR-Guided Cryoablation of Prostate Bed Recurrences

Mayo Clinic Source

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Other study identifiers

Sponsor study identifier

12-002245

Secondary identifiers

NCI-2023-01699

REGISTRY · CTRP (Clinical Trial Reporting Program)

Study Type

interventional

Estimated enrollment

200

Locations

1 country

Sites

1

Timeline

Study Start

December 12, 2012

Actual (reported)

Primary Completion

December 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

December 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Brief Summary

The purpose of this research is to see if MR-guided cryoablation can effectively treat prostate tumor recurrences.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: enrolling by invitation
Estimated enrollment: 200 participants
Study completion date: December 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
November 12, 2012
Actual (reported)
First Posted
November 15, 2012
Actual (reported)
Study Start
December 12, 2012
Actual (reported)
Primary Completion
December 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated: September 25, 2026
Status Verified: September 2026
Last Update Submitted: September 23, 2026

Conditions

Prostate Tumors

Outcome Measures

Primary Outcomes (1)

Evaluation of target lesion at 3-6, 12, 18, 24, and 36 month imaging follow-up
3 years

Study Arms (1)

MR-guided cryoablation (freezing of tissue and/or tumors)

EXPERIMENTAL

Patients undergo cryoablation using the Galil MR-compatible cryoablation system and MRI while on study.

Procedure: MR-guided cryoablation

Interventions

MR-guided cryoablationProcedure

MR-guided cryoablation (freezing of tissue and/or tumors)

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age30 Years - 100 Years

Sexmale

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Patients with "biopsy proven" soft tissue tumor or MRI/PET imaging convincing of recurrences of prostate fossa
Surgery is not a desirable alternative therapy at the time of enrollment

Sponsors & Collaborators

Mayo Clinic
Otherlead

Study Sites (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

David Woodrum, MD, PhD
Mayo Clinic
PRINCIPAL INVESTIGATOR

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Assistant Professor of Radiology

Study Record Dates

First Submitted

November 12, 2012

First Posted

November 15, 2012

Study Start

December 12, 2012

Actual (reported)

Primary Completion

December 2028

Estimated

Radiation therapy has failed or not indicated or can be safely postponed

Tumor size is \< 5 cm at its largest diameter

Tumor does not encompass the rectal wall or external urethral sphincter

Patient is able to undergo MRI

You may not qualify if:

N/A

Contact the study team to confirm eligibility.

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

December 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated

September 25, 2026

Record last verified: 2026-09

Data Sharing

IPD Sharing: Will not share

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT01727284
Data provider: ClinicalTrials.gov
Source updated: 2026-09-25
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:20:14 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

MR-guided cryoablation (freezing of tissue and/or tumors)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Links

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations