NCT01725867

Brief Summary

the purpose of this study is to compare the effect of physical therapy (PT) program and oral appliance on patients with temporomandibular disorder (TMD)-related myofascial pain (MFP).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2010

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 30, 2010

Completed
2 days until next milestone

Study Start

First participant enrolled

June 1, 2010

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2011

Completed
1.7 years until next milestone

First Posted

Study publicly available on registry

November 14, 2012

Completed
Last Updated

November 14, 2012

Status Verified

November 1, 2012

Enrollment Period

9 months

First QC Date

May 30, 2010

Last Update Submit

November 8, 2012

Conditions

Keywords

temporomandibular joint disordermyofascial painmanual myofascial releasephysical therapyoral appliance

Outcome Measures

Primary Outcomes (1)

  • Pain status

    Visual analog scale (VAS) during functional activity and pressure pain threshold (PPT) of masseter taut bands

    20 mins

Secondary Outcomes (5)

  • range of motion (ROM)

    5 mins

  • muscle strength

    5 mins

  • muscle endurance

    10 mins

  • muscle stiffness

    10 mins

  • Quality of life (QoL)

    15 mins

Other Outcomes (1)

  • stress

    5 mins

Study Arms (2)

PT program

EXPERIMENTAL

manual myofascial release for craniomandibular system for 30\~40 minutes chin-in exercise within 10 minutes and as home exercise self-care education twice per week for 8 weeks

Other: PT program

Splint group

ACTIVE COMPARATOR

custom-made oral appliance: wear every night for 8 weeks, occasional drop is allowed self-care education

Device: oral appliance

Interventions

manual myofascial release for craniomandibular system for 30\~40 minutes chin-in exercise within 10 minutes and as home exercise self-care education twice per week for 8 weeks

PT program

custom-made oral appliance: wear every night for 8 weeks, occasional drop is allowed self-care education

Splint group

Eligibility Criteria

Age20 Years - 65 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • (1) 20-65 years old female, (2) diagnosed as MFP subtype of TMD according to Research Diagnostic Criteria for TMD (RDC/TMD), (3) pain duration over 3 month, (4) palpable taut band in masseter, (5) Asymmetrical pain intensity, (6) subsided symptoms of joint inflammation.

You may not qualify if:

  • (1) traumatic TMD from external impact force, (2) history of traumatic cervical injury, (3) presence of systemic disease, (4) fibromyalgia, (5) co-interventions for cervical problems or TMD during study period, (6) signs of psychosomatic illness, (7) unwilling to be randomized, (8) unable to wear the splint or received intraoral myofascial release, (9)pregnancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, 100, Taiwan

Location

MeSH Terms

Conditions

Temporomandibular Joint Disorders

Condition Hierarchy (Ancestors)

Craniomandibular DisordersMandibular DiseasesJaw DiseasesMusculoskeletal DiseasesJoint DiseasesMuscular DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
National Taiwan University Hospital

Study Record Dates

First Submitted

May 30, 2010

First Posted

November 14, 2012

Study Start

June 1, 2010

Primary Completion

March 1, 2011

Study Completion

March 1, 2011

Last Updated

November 14, 2012

Record last verified: 2012-11

Locations