NCT01714882

Brief Summary

The investigators are trying to determine stress management strategies in couples undergoing In Vitro Fertilization (IVF).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Oct 2012

Typical duration for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2012

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

October 18, 2012

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 26, 2012

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
Last Updated

November 6, 2015

Status Verified

November 1, 2015

Enrollment Period

2.9 years

First QC Date

October 18, 2012

Last Update Submit

November 5, 2015

Conditions

Keywords

InfertilityIn Vitro Fertilization (IVF)Stress ManagementStress Reduction

Outcome Measures

Primary Outcomes (1)

  • Change of Scores from questionnaires from baseline to 6 and then 12 weeks

    Primary outcome measure will be comparison of pre- and post-stress reduction treatment questionnaire scale scores.

    Baseline, 6 and 12 weeks after randomization

Secondary Outcomes (1)

  • Clinical Pregnancy rate

    12 months after randomization

Other Outcomes (1)

  • Clinical or biochemical miscarriage

    12 months after randomization

Study Arms (2)

Stress Management & Resiliency Training

EXPERIMENTAL

The couples in this group will attend the SMART in-person training class at the beginning of the study and will be taught a structured relaxation program.

Behavioral: Stress Management & Resiliency Training

Stress Management DVD

ACTIVE COMPARATOR

The couples in this group will receive a Mayo Clinic Stress Management DVD.

Behavioral: Stress Management DVD

Interventions

The couples in this group will attend the SMART in-person training class at the beginning of the study and will be taught a structured relaxation program.

Stress Management & Resiliency Training

The couples in this group will receive a Mayo Clinic Stress Management DVD.

Stress Management DVD

Eligibility Criteria

Age18 Years - 39 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Women with clinical infertility, either primary or secondary, who are recommended for IVF for the first time as part of their treatment for infertility
  • Women with a partner, and both are willing to provide consent for study participation as a couple
  • Couples that can be reached by telephone for follow-up

You may not qualify if:

  • Women less than 18 years of age
  • Women equal or greater than 40 years of age
  • Women with a history of recurrent pregnancy loss
  • History of current or recent psychotic episode within past 6 months for either the woman or her partner
  • Couples needing a interpreter for their clinical encounter

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

  • Amit Sood, MD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR
  • Zaraq Khan, MBBS

    Mayo Clinic

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor of Medicine, Consultant - General Internal Medicine

Study Record Dates

First Submitted

October 18, 2012

First Posted

October 26, 2012

Study Start

October 1, 2012

Primary Completion

September 1, 2015

Study Completion

September 1, 2015

Last Updated

November 6, 2015

Record last verified: 2015-11

Locations