Multi-Component Technology Intervention for Minority Emerging Adults With Asthma

NCT01714141 | Completed DMC

• 1 other identifier: MCTI-1R34HL107664-01A1
• Study Type: interventional
• Target: 48
• Locations: 0 countries
• Sites: N/A

Brief Summary

This pilot study's main goal is to develop and preliminarily test a technology-based intervention to improve asthma medication adherence in urban African American emerging adults (ages 18-29). It is hypothesized that youth randomized to MCTI for adherence will show improvements in motivation to adhere to asthma medications and self-reported adherence compared to the comparison condition at 1- and 3- month follow up.

Conditions

Asthma; Poor Medication Adherence

Keywords

Technology based intervention; Emerging adults; African Americans; Asthma; Controller medications; Motivational intervention

Outcome Measures

Primary Outcomes (2)

• Change in medication adherence

  Self-reported adherence to asthma controller medication(s) through questionnaire report and, at baseline and 3 months, 7 days of momentary (real time) sampling of adherence behavior via SMS text messaging.

  baseline, 1 month, 3 month

• Change in motivation for medication adherence

  Self-report of motivation to take asthma controller medications as prescribed.

  baseline, 1 month, 3 month

Secondary Outcomes (7)

• Change in asthma knowledge

  baseline, 1 month, 3 month

• Change in asthma medication confidence

  Baseline, 1 month, 3 month

• Change in asthma medication importance

  baseline, 1 month, 3 month

• Change in asthma control

  baseline, 1 month, 3 month

• Change in barriers to taking medication

  baseline, 1 month, 3 months

Study Arms (2)

Multi-component, technology based intervention

EXPERIMENTAL

2 tailored, computer-delivered motivational interviewing sessions targeting adherence to asthma control medications + tailored text messaged reminders to take medications between sessions.

Behavioral: Multi-component, technology based intervention

Asthma education active control

ACTIVE COMPARATOR

Control condition consists of active control matched to intervention for delivery-method and time-- 2 sessions of computer-delivered asthma education + daily text messaged facts about asthma.

Behavioral: Asthma education active control

Interventions

Multi-component, technology based intervention BEHAVIORAL

Motivational sessions were adapted from work done with young adults with HIV (MESA).

Multi-component, technology based intervention

Asthma education active control BEHAVIORAL

Asthma education active control

Eligibility Criteria

• Age: 18 Years - 29 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• African American Live in the Detroit Area, approximately 30 miles from the Hutzel Building Ages 18-29
• Have moderate to severe persistent asthma. Persistent asthma is defined according to the 2007 NHLBI guidelines. The level of symptoms, as defined by any of the following in the last 4 weeks:
• Use of any asthma medication more than 2 times a week Daytime asthma symptoms such as wheezing, tightness of chest, problems coughing more than 2 times a week, or waking up at night because of asthma more than 2 times a month
• Participant is prescribed a daily asthma controller medication, even if they do not take it.
• Participant must report poor adherence to daily controller medications during eligibility screening (brief interview).
• Poor adherence is defined as not taking medications "as prescribed" less than 4 days per week in any of the 4 weeks prior to enrollment OR as a proxy of poor adherence as self-report of \<80% medication adherence in the past 30 days, self-report of emergency room visit/hospitalization for asthma in the past 6 months, or a poor score on the Asthma Control Test.

You may not qualify if:

• Individuals with other chronic health conditions requiring ongoing medical intervention ( e.g., HIV, Type II Diabetes) will be excluded.
• These chronic diseases include: Glaucoma, bi-polarism, segmented glomerular nephritis, cystic fibrosis, spondyloarthropathy, congenital heart disease, sickle cell
• No pregnant women will be included in this study.

Sponsors & Collaborators

• Wayne State University: lead

Related Publications (1)

• Kolmodin MacDonell K, Naar S, Gibson-Scipio W, Lam P, Secord E. The Detroit Young Adult Asthma Project: Pilot of a Technology-Based Medication Adherence Intervention for African-American Emerging Adults. J Adolesc Health. 2016 Oct;59(4):465-71. doi: 10.1016/j.jadohealth.2016.05.016. Epub 2016 Jul 27.

  PMID: 27475032 RESULT

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistante Professor

Study Record Dates

• First Submitted: October 17, 2012
• First Posted: October 25, 2012
• Study Start: December 1, 2011
• Primary Completion: September 1, 2015
• Study Completion: September 1, 2015
• Last Updated: November 1, 2016

Record last verified: 2016-10