NCT01713322

Brief Summary

Immunization procedures are a common source of iatrogenic pain for infants. A recently developed clinical practice guideline, led by Taddio et al., created evidence-based strategies for management of immunization pain. User-friendly educational tools outlining these strategies were made. The goal of cluster randomized controlled trial is to assess whether these educational materials increase utilization of pain-relieving strategies by parents during infant immunizations.

Trial Health

55
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P25-P50 for phase_3

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 21, 2012

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 24, 2012

Completed
8 days until next milestone

Study Start

First participant enrolled

November 1, 2012

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2013

Completed
Last Updated

December 24, 2012

Status Verified

December 1, 2012

Enrollment Period

10 months

First QC Date

October 21, 2012

Last Update Submit

December 21, 2012

Conditions

Keywords

parent educationpain managementimmunizationinfant

Outcome Measures

Primary Outcomes (1)

  • Number of pain management strategies utilized

    The number of pain management strategies utilized during immunization injections measured post-intervention from videotapes by a blinded assessor.

    During immunization

Secondary Outcomes (6)

  • Pain during infant immunizations

    During immunization

  • Parent behaviour during infant immunizations

    During immunization

  • Pain during infant immunizations as reported by parents

    During immunization

  • Parent-reported satisfaction with immunization experience

    During immunization

  • Duration of infant crying during immunizations

    During immunization

  • +1 more secondary outcomes

Study Arms (2)

Pain management education

EXPERIMENTAL

Parents are provided with educational material on how to manage child pain during immunization.

Behavioral: Pain management education

No pain management education

OTHER

Control - parents receive general information about childhood immunization.

Behavioral: No pain management education

Interventions

Parents are provided with educational material on how to manage child pain during immunization.

Pain management education

Control - parents receive general information about childhood immunization.

No pain management education

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Parents of 2 or 4-month old healthy infants during routine immunization appointments
  • Parent accompanies infant at immunization appointments

You may not qualify if:

  • Parents of infants \<30 weeks gestational age (GA)
  • Parents delaying infant immunization for \>2 months
  • Parents who are unable to read and understand English
  • Infants with congenital anomalies, neurological conditions, and maternal psychiatric conditions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St. Michael's Health Center, Pediatric Clinic.

Toronto, Ontario, M5B 1W8, Canada

RECRUITING

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Anna Taddio, PhD

    University of Toronto

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Michael Sgro, MD

CONTACT

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 21, 2012

First Posted

October 24, 2012

Study Start

November 1, 2012

Primary Completion

September 1, 2013

Last Updated

December 24, 2012

Record last verified: 2012-12

Locations