NCT01710384

Brief Summary

To test the effect on premature infants of a one-time course of betamethasone administered in weeks 34-36 of gestation.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Nov 2012

Typical duration for phase_2

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 17, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 19, 2012

Completed
13 days until next milestone

Study Start

First participant enrolled

November 1, 2012

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2014

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
Last Updated

October 19, 2012

Status Verified

October 1, 2012

Enrollment Period

2 years

First QC Date

October 17, 2012

Last Update Submit

October 17, 2012

Conditions

Keywords

late preterm, betamethasone,

Outcome Measures

Primary Outcomes (1)

  • neonate respiratory distress syndrome

    1 year

Secondary Outcomes (1)

  • 1 and 5 minute Apgar scores, and complications during the first week of life, including hypoglycemia, seizures, intubation or medications

    1 week

Study Arms (2)

betamethasoneb, 34-36 weeks, preterm labor

EXPERIMENTAL

betamethasone 12 mg 2 injections will be given 24-hours apart.

Drug: betamethasone

preterm labor, 34-37 weeks

NO INTERVENTION

betamethasone 12 mg 2 injections will be given 24-hours apart.

Interventions

betamethasoneb, 34-36 weeks, preterm labor

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • \. Pregnant woman in weeks 34-36 of gestation who did not receive a betamethasone course to enhance fetal lung maturity during pregnancy 2. Clinical, sonographic or laboratory suspicion of premature labor 3. Singleton or twin pregnancy

You may not qualify if:

  • Premature rupture of membranes
  • Fetus with known defects
  • Suspicion of fetal distress
  • Betamethasone administered during pregnancy for any reason

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Betamethasone

Intervention Hierarchy (Ancestors)

PregnadienetriolsPregnadienesPregnanesSteroidsFused-Ring CompoundsPolycyclic CompoundsSteroids, Fluorinated

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 17, 2012

First Posted

October 19, 2012

Study Start

November 1, 2012

Primary Completion

November 1, 2014

Study Completion

November 1, 2015

Last Updated

October 19, 2012

Record last verified: 2012-10