Effects of Legumes on Glucose Regulation
Over-night Metabolic Effects of Legumes
1 other identifier
interventional
16
1 country
1
Brief Summary
Dietary prevention strategies are increasingly recognized as essential to combat the current epidemic of obesity and related metabolic disorders. The purpose of the present study was to evaluate the potential effects of legumes in relation to cardiometabolic risk markers and appetite regulating hormones.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2010
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2011
CompletedFirst Submitted
Initial submission to the registry
October 10, 2012
CompletedFirst Posted
Study publicly available on registry
October 15, 2012
CompletedOctober 15, 2012
October 1, 2012
6 months
October 10, 2012
October 12, 2012
Conditions
Outcome Measures
Primary Outcomes (1)
blood glucose
A portion of legumes or bread was consumed as a late evening meal, blood glucose was measured the next morning at breakfast.
11 hours
Secondary Outcomes (1)
satiety
11 hours
Other Outcomes (1)
inflammatory markers
11 hours
Study Arms (2)
white bread
PLACEBO COMPARATORWhite bread (based on 35 g available carbohydrates)
Legume meal
ACTIVE COMPARATORLegumes are consumed as a late evening meal(based on 35 g available carbohydrates)
Interventions
Eligibility Criteria
You may qualify if:
- Healthy subjects between 20-35 years
- With normal BMI and
- No known metabolic- or gastro intestinal disease
You may not qualify if:
- BMI \> 25,
- Known metabolic disorder or
- Gastrointestinal problems or disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Lund Universitylead
- Anti-Diabetic Food Centrecollaborator
Study Sites (1)
Applied Nutrition and Food Chemistry, Lund University
Lund, SE-22100, Sweden
Related Publications (3)
Sievenpiper JL, Kendall CW, Esfahani A, Wong JM, Carleton AJ, Jiang HY, Bazinet RP, Vidgen E, Jenkins DJ. Effect of non-oil-seed pulses on glycaemic control: a systematic review and meta-analysis of randomised controlled experimental trials in people with and without diabetes. Diabetologia. 2009 Aug;52(8):1479-95. doi: 10.1007/s00125-009-1395-7. Epub 2009 Jun 13.
PMID: 19526214BACKGROUNDPapanikolaou Y, Fulgoni VL 3rd. Bean consumption is associated with greater nutrient intake, reduced systolic blood pressure, lower body weight, and a smaller waist circumference in adults: results from the National Health and Nutrition Examination Survey 1999-2002. J Am Coll Nutr. 2008 Oct;27(5):569-76. doi: 10.1080/07315724.2008.10719740.
PMID: 18845707BACKGROUNDNilsson A, Johansson E, Ekstrom L, Bjorck I. Effects of a brown beans evening meal on metabolic risk markers and appetite regulating hormones at a subsequent standardized breakfast: a randomized cross-over study. PLoS One. 2013;8(4):e59985. doi: 10.1371/journal.pone.0059985. Epub 2013 Apr 5.
PMID: 23577078DERIVED
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- assistant lector
Study Record Dates
First Submitted
October 10, 2012
First Posted
October 15, 2012
Study Start
February 1, 2010
Primary Completion
August 1, 2010
Study Completion
August 1, 2011
Last Updated
October 15, 2012
Record last verified: 2012-10