Determination of Drugs and Their Metabolites in Hospitalized Patients
1 other identifier
observational
1,000
1 country
1
Brief Summary
The current state of knowledge on the concentration of drugs and their metabolites in the individual human body is not satisfying concerning the question about behavior of drugs in the human body, taking into account individual patient factors such as age, weight and organ dysfunctions. This projects deals with the question of drug levels in the blood of hospitalized patients. The aim of this study is to extend the knowledge about the behavior of drugs in the human body significantly, for the safety and benefit of future patients. This also includes to establish a relationship between drug levels in patients and the desired and undesired effects of a drug. As a result, the future perspective is to find the optimal dose for the individual patient by measuring the blood concentration of a drug.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2012
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2012
CompletedFirst Submitted
Initial submission to the registry
October 1, 2012
CompletedFirst Posted
Study publicly available on registry
October 8, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2021
CompletedSeptember 2, 2020
September 1, 2020
9.3 years
October 1, 2012
September 1, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Plasma concentrations [ng/mL] of various drugs at different timepoints
up to five years
Eligibility Criteria
Hospitalized patients
You may qualify if:
- legal capacity
You may not qualify if:
- severe anemia
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Dept. of Internal Medicine V, Klinikum Nürnberg Nord
Nuremberg, Bavaria, 90419, Germany
Biospecimen
Blood, Plasma
MeSH Terms
Conditions
Study Officials
- STUDY CHAIR
Martin Wilhelm, Prof Dr.
Paracelsus Medical University Klinikum Nuremberg, Germany
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Prof. Dr. med. Martin Wilhelm
Study Record Dates
First Submitted
October 1, 2012
First Posted
October 8, 2012
Study Start
August 1, 2012
Primary Completion
December 1, 2021
Study Completion
December 1, 2021
Last Updated
September 2, 2020
Record last verified: 2020-09