Difference Between Central and Peripheral Arterial Blood Oxygen Saturation With Different CPB Strategy
The Difference Between Central and Peripheral Arterial Blood Oxygen Saturation in Patients Undergoing Cardiac Surgery With Different Cardiopulmonary Bypass Strategy
1 other identifier
observational
60
1 country
1
Brief Summary
Femoro-femoral cardiopulmonary bypass with retrograde perfusion is needed for totally thoracoscopic cardiac surgery. one of the major complication of retrograde perfusion is organ hypoperfusion. Arterial blood gas analysis can help to detect hypoperfusion or hypoxia during retrograde perfusion. However,whether the arterial oxygenation status from different parts of the body are the same in the condition of retrograde perfusion have not been studied. The present study is aimed to determine if there is difference in the arterial oxygenation between peripheral arterial and aortic root during the period of retrograde perfusion.In addition, the impact of artificial ventilation on the difference of arterial oxygenation will also be investigated.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Oct 2012
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 25, 2012
CompletedStudy Start
First participant enrolled
October 1, 2012
CompletedFirst Posted
Study publicly available on registry
October 3, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2013
CompletedOctober 3, 2012
September 1, 2012
5 months
September 25, 2012
September 29, 2012
Conditions
Outcome Measures
Primary Outcomes (1)
The difference between peripheral arterial oxygenation and aortic root blood oxygenation
The three time points for blood sample collection are:1.right before clamping the aorta; 2.Three minutes after \*\*\*\* without ventilation;3.5 min after re-initiate mechanical ventilation.
patients will be followed up during the cardiopulmonary bypass. Blood samples will be collected at 3 timepoints which is specified in the DESCRIPTION
Eligibility Criteria
patient undergoing totally thoracoscopic cardiac surgery with cardiopulmonary bypass
You may qualify if:
- age \> 18 years old
- undergoing totally thoracoscopic cardiac surgery with cardiopulmonary bypass
You may not qualify if:
- without informed consent
- pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Xijing Hospitallead
Study Sites (1)
Department of Anesthesiology, Xijing Hospital
Xi'an, Shaanxi, 710032, China
Study Officials
- STUDY CHAIR
Hailong Dong, Doctor
department director
Central Study Contacts
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 25, 2012
First Posted
October 3, 2012
Study Start
October 1, 2012
Primary Completion
March 1, 2013
Study Completion
May 1, 2013
Last Updated
October 3, 2012
Record last verified: 2012-09