NCT01695382

Brief Summary

Palliative care is a priority area of focus for health care in an aging population experiencing burdens of chronic illness. Despite the evidence-based benefits of palliative care, access remains limited, especially in poor urban and rural settings. Cultural and linguistic barriers may also increase disparities in palliative care for Latinos. Due to a nationwide shortage of palliative care providers and the unique cultural preferences and values of patients, the investigators are testing a patient navigator intervention to improve palliative care outcomes for Latinos with advanced cancer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
223

participants targeted

Target at P75+ for not_applicable cancer

Timeline
Completed

Started Aug 2012

Longer than P75 for not_applicable cancer

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2012

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 25, 2012

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 28, 2012

Completed
4.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

February 3, 2017

Status Verified

February 1, 2017

Enrollment Period

4.3 years

First QC Date

September 25, 2012

Last Update Submit

February 1, 2017

Conditions

Keywords

CancerPalliative CarePatient Navigation

Outcome Measures

Primary Outcomes (4)

  • Improvement in Palliative Care Overall

    Patient Navigator and Process Measure will capture the less tangible benefits of a patient navigator and help understand the effects of the many activities of the navigator beyond the scope of the prescribed intervention. The questions incorporate aspects of self-efficacy and patient activation (key concepts that patient navigators help improve).

    3 months after enrollment

  • Evidence of Advance Care Planning

    Chart review to determine if there is an advance directive in the medical record and classification of the type of advance directive (Medical Durable Power of Attorney (MDPOA), Advance Directive (AD), Living Will)

    6 months after enrollment

  • Assesment of Pain Management

    Pain management will be assessed through patient interviews utilizing the Brief Pain Inventory (BPI). The BPI Long Form (BPI-LF) is a 32-item self-report instrument that assesses the severity and impact of pain in patients with chronic diseases, e.g. cancer.

    3 months after enrollment

  • Hospice Utilization

    Length of stay in hospice program in days. Data will be collected through follow up phone calls, medical records review, and death records review to determine date of admission into hospice program and date of discharge (through death or dis-enrollment)

    46 months after enrollment

Secondary Outcomes (2)

  • Aggressiveness of Care at the End of Life

    At month 46

  • Change in Quality of Life

    Baseline and 3 months after enrollment

Study Arms (2)

Navigation

EXPERIMENTAL

Participants randomized to the control arm of the study will receive a packet of written materials that are appropriate linguistically and written for individuals with low health literacy. In addition they will have 5 navigator initiated home visits to review the educational materials and help patients and families address barriers to palliative care through education, advocacy, and activation.

Behavioral: Navigation

Control

NO INTERVENTION

Participants randomized to the control arm of the study will receive a packet of written materials that are appropriate linguistically and written for individuals with low health literacy.

Interventions

NavigationBEHAVIORAL

As per Arm description

Navigation

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Stage III or Stage IV cancer (all types)
  • Self-identify as Latino
  • years of age or older
  • Speak English or Spanish

You may not qualify if:

  • Lacking decisional capacity
  • Incarcerated

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

San Luis Valley Regional Medical Center

Alamosa, Colorado, 81101, United States

Location

University of Colorado Cancer Center

Aurora, Colorado, 80045, United States

Location

Denver Health and Hospital Authority

Denver, Colorado, 80202, United States

Location

Shaw Cancer Center

Eagle, Colorado, 81632, United States

Location

Valley View Medical Center

Glenwood Springs, Colorado, 81601, United States

Location

Related Publications (2)

  • Fischer SM, Kline DM, Min SJ, Okuyama-Sasaki S, Fink RM. Effect of Apoyo con Carino (Support With Caring) Trial of a Patient Navigator Intervention to Improve Palliative Care Outcomes for Latino Adults With Advanced Cancer: A Randomized Clinical Trial. JAMA Oncol. 2018 Dec 1;4(12):1736-1741. doi: 10.1001/jamaoncol.2018.4014.

  • Fischer SM, Kline DM, Min SJ, Okuyama S, Fink RM. Apoyo con Carino: Strategies to Promote Recruiting, Enrolling, and Retaining Latinos in a Cancer Clinical Trial. J Natl Compr Canc Netw. 2017 Nov;15(11):1392-1399. doi: 10.6004/jnccn.2017.7005.

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Stacy M Fischer, MD

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 25, 2012

First Posted

September 28, 2012

Study Start

August 1, 2012

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

February 3, 2017

Record last verified: 2017-02

Locations