NCT01693016

Brief Summary

The purpose of this study is to evaluate the value of the new technique of non-invasive measurement of Hb in children undergoing a surgical procedure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
81

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2012

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

September 19, 2012

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 26, 2012

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2013

Completed
Last Updated

March 26, 2014

Status Verified

March 1, 2014

Enrollment Period

4 months

First QC Date

September 19, 2012

Last Update Submit

March 23, 2014

Conditions

Keywords

non-invasive Hb measurement in children

Outcome Measures

Primary Outcomes (1)

  • correlation between SpHb(®) and the Hb measured by the ABL800Flex and the Siemens Advia

    one day

Secondary Outcomes (1)

  • influence of inhalation anesthetics

    one day

Study Arms (2)

inhalation group

OTHER

20 children Taking blood samples and SpHb-measurement was made under inhalational anesthesia

Device: non-invasive measurement of HbProcedure: taking blood samples

non-inhalational

OTHER

40 children Taking blood samples and SpHb measurements in awake and spontaneous breathing children.

Device: non-invasive measurement of HbProcedure: taking blood samples

Interventions

Also known as: SpHb (®) by Masimo ® Radical 7
inhalation groupnon-inhalational
Also known as: blood for BGA (ABL 800), blood for laboratory Hb (Siemens Advia)
inhalation groupnon-inhalational

Eligibility Criteria

AgeUp to 8 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • children (\>= 3 kg until 8 years)
  • ASA I-III
  • written informed consent of legal representative

You may not qualify if:

  • children \<= 3kg or \> 8 years
  • emergency surgery
  • allergy against sensor of SpHb(®)
  • artery occlusive disease
  • sepsis
  • haemoglobinopathy
  • specific medical or psychological circumstances which do not allow the consent of the legal representative or the performance of the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dr. Eva Wittenmeier

Mainz, 55131, Germany

Location

Related Publications (1)

  • Wittenmeier E, Bellosevich S, Mauff S, Schmidtmann I, Eli M, Pestel G, Noppens RR. Comparison of the gold standard of hemoglobin measurement with the clinical standard (BGA) and noninvasive hemoglobin measurement (SpHb) in small children: a prospective diagnostic observational study. Paediatr Anaesth. 2015 Oct;25(10):1046-53. doi: 10.1111/pan.12683. Epub 2015 Jul 14.

MeSH Terms

Interventions

Blood Specimen Collection

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Study Officials

  • Eva Wittenmeier

    Johannes Gutenberg University Mainz

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Eva Wittenmeier

Study Record Dates

First Submitted

September 19, 2012

First Posted

September 26, 2012

Study Start

September 1, 2012

Primary Completion

January 1, 2013

Study Completion

January 1, 2013

Last Updated

March 26, 2014

Record last verified: 2014-03

Locations