Effects of Milk Protein Concentrate on Overall Health During Weight Loss in Overweight/Obese Adults

NCT01692860 | Completed

• 1 other identifier: 1109011319
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

. The purpose of this study is to examine the effects of eating a larger amount of dairy-based protein on risk factors for metabolic syndrome

Conditions

Sarcopenia; Metabolic Disease; High Blood Pressure

Keywords

the impact of a higher dairy-based protein diet in; combination with energy restriction on muscle health,; metabolic health (including blood pressure) in overweight; and obese, middle aged adults

Outcome Measures

Primary Outcomes (1)

• weight loss

  20 weeks

Study Arms (2)

High protein consumption

EXPERIMENTAL

Intervention, energy restriction. This arm has a dietary protein intake of 1.5g/kg/d

Other: Energy Restriction

Normal protein consumption

PLACEBO COMPARATOR

Intervention, energy restriction. This arm has a dietary protein intake of .8g/kg/d

Other: Energy Restriction

Interventions

Energy Restriction OTHER

Subjects consume 750 kcal/d of energy below their need

High protein consumption; Normal protein consumption

Eligibility Criteria

• Age: 35 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• BMI: 25-38 ,male or female; age 35-65 y; weight stable (± 3 kg) during last 3 months; no acute illness; not diabetic, pregnant or lactating; not currently (or within last 3 months) following an exercise or weight loss program; non-smoking; not taking BP medication; not lactose intolerant,

You may not qualify if:

• Subjects will be excluded if baseline protein intake is less than 0.6 or greater than 1.6 g•kg-1•d-1 Subjects will also be excluded if they have any chronic or acute condition which will increase risk of illness or injury during study participation as determined by our study physician such as high BP, high fasting glucose, metabolic syndrome, etc.

Sponsors & Collaborators

• Purdue University: lead

Study Sites (1)

Purdue University - Stone Hall 700 W State St

West Lafayette, Indiana, 47907, United States

Location

Related Publications (1)

• Zhou J, Kim JE, Armstrong CL, Chen N, Campbell WW. Higher-protein diets improve indexes of sleep in energy-restricted overweight and obese adults: results from 2 randomized controlled trials. Am J Clin Nutr. 2016 Mar;103(3):766-74. doi: 10.3945/ajcn.115.124669. Epub 2016 Feb 10.

  PMID: 26864362 DERIVED

MeSH Terms

Conditions

Sarcopenia; Metabolic Diseases; Hypertension; Obesity

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Nutritional and Metabolic Diseases; Vascular Diseases; Cardiovascular Diseases; Overweight; Overnutrition; Nutrition Disorders; Body Weight

Study Officials

• Wayne W Campbell, Ph. D.

  Purdue University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Wayne Campbell, Ph.D.

Study Record Dates

• First Submitted: September 21, 2012
• First Posted: September 25, 2012
• Study Start: January 1, 2012
• Primary Completion: September 1, 2014
• Study Completion: January 1, 2015
• Last Updated: November 4, 2015

Record last verified: 2015-11

Locations

US (1)