NCT01690494

Brief Summary

This study is a randomized controlled trial (RCT) that will rigorously evaluate the implementation, effectiveness and cost-effectiveness of a couple-based integrated human immunodeficiency virus (HIV) and drug abuse prevention intervention (Connect II) with drug-involved male offenders charged with misdemeanors and their primary female sexual partners, implemented by frontline providers in Criminal Court, Community Court or probation (CCP) sites in NYC, compared to CCP standard treatment of care services (TAU). The primary outcomes are to reduce sexually transmitted infections (STIs) and increase condom use.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
480

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2013

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 19, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 21, 2012

Completed
9 months until next milestone

Study Start

First participant enrolled

June 11, 2013

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2017

Completed
Last Updated

July 18, 2018

Status Verified

July 1, 2018

Enrollment Period

4.3 years

First QC Date

September 19, 2012

Last Update Submit

July 16, 2018

Conditions

Keywords

STIsexually transmitted infectionHIVcriminal justiceprobationcouplesdrug use

Outcome Measures

Primary Outcomes (2)

  • Change in biologically confirmed sexually transmitted infections

    Baseline and up to 12 months post intervention

  • Change in proportion of unprotected sexual acts

    Baseline and up to 12 months post intervention

Secondary Outcomes (3)

  • Change in drug use

    Baseline and up to 12 months post intervention

  • Change in utilization of drug treatment

    Baseline and up to 12 months post intervention

  • Change in recidivism

    Up to 12 months post intervention

Study Arms (2)

PACT + TAU

EXPERIMENTAL

4-session PACT delivered to both partners together + standard treatment of care services (TAU) delivered to the male participant

Behavioral: PACTBehavioral: TAU

TAU

ACTIVE COMPARATOR

TAU control condition delivered to the male participant

Behavioral: TAU

Interventions

PACTBEHAVIORAL

Couple-based behavioral HIV/STI preventive intervention

PACT + TAU
TAUBEHAVIORAL

Standard treatment of care services provided to male offenders by the Criminal Court, Community Court or probation sites

PACT + TAUTAU

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Couples
  • Both partners are aged 18 or older
  • Identify each other as their primary sexual partner of opposite sex
  • Relationship has existed at least 3 months
  • At least one partner reports having unprotected vaginal or anal intercourse with the other partner in the past 90 days
  • At least one partner reports exposure to an outside HIV risk in the past year
  • Male partner reports and is verified by court records of being charged with a misdemeanor
  • Male partner is currently under court supervision or probation

You may not qualify if:

  • Either partner shows evidence of significant psychiatric or could impairment as confirmed by the MacArthur Competence Assessment Tool during the screening eligibility interview.
  • Either partner reports severe physical or sexual violence perpetrated by the other partner in the past year as measured on the Revised Conflict Tactics Scale
  • Either partner is unable to commit to participate in the study through to completion
  • Either partner reports that the couple is planning a pregnancy within the next 12 months
  • Either partner is not fluent in English as determined during Informed Consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Columbia University

New York, New York, 10027, United States

Location

Related Publications (3)

  • El-Bassel N, Gilbert L, Wu E, Witte SS, Chang M, Hill J, Remien RH. Couple-based HIV prevention for low-income drug users from New York City: a randomized controlled trial to reduce dual risks. J Acquir Immune Defic Syndr. 2011 Oct 1;58(2):198-206. doi: 10.1097/QAI.0b013e318229eab1.

    PMID: 21725249BACKGROUND
  • Wimberly AS, Rose R, Levin K, Goddard-Eckrich D, Gilbert L, Wu E, Dasgupta A, Hunt T, Henry BF, El-Bassel N. Traumatic Life Events and Stressors: Associations With Substance Use Problems of Men Under Community Supervision. J Correct Health Care. 2023 Jun;29(3):190-197. doi: 10.1089/jchc.21.12.0137. Epub 2023 Apr 28.

  • El-Bassel N, Gilbert L, Goddard-Eckrich D, Chang M, Wu E, Goodwin S, Tibbetts R, Almonte-Weston M, Hunt T. Effectiveness of a Couple-Based HIV and Sexually Transmitted Infection Prevention Intervention for Men in Community Supervision Programs and Their Female Sexual Partners: A Randomized Clinical Trial. JAMA Netw Open. 2019 Mar 1;2(3):e191139. doi: 10.1001/jamanetworkopen.2019.1139.

MeSH Terms

Conditions

Sexually Transmitted DiseasesUnsafe SexSubstance-Related Disorders

Condition Hierarchy (Ancestors)

Communicable DiseasesInfectionsGenital DiseasesUrogenital DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsSexual BehaviorBehaviorChemically-Induced DisordersMental Disorders

Study Officials

  • Nabila El-Bassel, DSW

    Columbia University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Social Work

Study Record Dates

First Submitted

September 19, 2012

First Posted

September 21, 2012

Study Start

June 11, 2013

Primary Completion

September 30, 2017

Study Completion

September 30, 2017

Last Updated

July 18, 2018

Record last verified: 2018-07

Locations