Diagnostic and Prognostic Value of Combination Biomarkers in the Critically Ill Patient With Sepsis.
1 other identifier
observational
300
1 country
1
Brief Summary
Sepsis is a common cause for morbidity and mortality in critically ill patients. With the development of medical skills, the mortality is still remain very high. Inappropriateness of initial antibiotic treatment is an important risk factor for mortality and effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock. However, the early treatment based on early diagnosis.But it is very difficult to diagnosis because of lack of specific clinic symptom and sign.When severe sepsis occur, biomarker could be helpful to diagnosis. Unfortunately, the diagnostic value of single biomarker is limited. Therefore, combine several biomarkers could enhance the diagnostic value.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2012
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2012
CompletedFirst Submitted
Initial submission to the registry
September 13, 2012
CompletedFirst Posted
Study publicly available on registry
September 18, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2012
CompletedSeptember 18, 2012
August 1, 2012
September 13, 2012
September 17, 2012
Conditions
Keywords
Eligibility Criteria
Critically ill patients
You may qualify if:
- Critically ill patients admitted into ICU
You may not qualify if:
- Age younger than 18 years
- Refuse to participate in this study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Jianfeng Xielead
- Southeast University, Chinacollaborator
Study Sites (1)
Department of Critical Care Medicine Nanjing Zhong-da Hospital Southeast University School of Medicine
Nanjing, Jiangsu, 210009, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Physician of critical care department
Study Record Dates
First Submitted
September 13, 2012
First Posted
September 18, 2012
Study Start
March 1, 2012
Study Completion
October 1, 2012
Last Updated
September 18, 2012
Record last verified: 2012-08