NCT01686516

Brief Summary

Diffusion MRI employed in functional imaging has the potential to probe directly brain activation instead of blood changes like the BOLD technique. The researchers investigated these rapid synaptic plasticity changes with visual activation followed by BOLD and diffusion functional MRI as well as anatomical (venography, tractography by diffusion) features in young and aged subjects.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Dec 2011

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 5, 2011

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

September 7, 2012

Completed
11 days until next milestone

First Posted

Study publicly available on registry

September 18, 2012

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 19, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 19, 2012

Completed
Last Updated

March 5, 2025

Status Verified

March 1, 2025

Enrollment Period

10 months

First QC Date

September 7, 2012

Last Update Submit

March 3, 2025

Conditions

Brain Aging

Keywords

agemicrostructurediffusion MRI

Eligibility Criteria

Age20 Years - 80 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

population free of any psychological or organic troubles, with no metal inclusions for MRI convenience.

You may qualify if:

  • ages 20-30 years
  • years

You may not qualify if:

  • psychological or organic trouble

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Inserm U 825

Toulouse, France, 31059, France

Location

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 7, 2012

First Posted

September 18, 2012

Study Start

December 5, 2011

Primary Completion

September 19, 2012

Study Completion

September 19, 2012

Last Updated

March 5, 2025

Record last verified: 2025-03

Locations

FR(1)