NCT01685164

Brief Summary

As intrauterine contraception is an increasingly popular form of contraception the objective of our study is to examine if uterine size or posture affects the insertion or use of intrauterine devices. Nulliparous women requesting either the levonorgestrel-releasing device (LNG-IUS) or a copper-IUD (NovaT) are recruited and followed for one year.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
161

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2011

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2011

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

August 30, 2012

Completed
15 days until next milestone

First Posted

Study publicly available on registry

September 14, 2012

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2013

Completed
Last Updated

February 23, 2018

Status Verified

February 1, 2018

Enrollment Period

2.5 years

First QC Date

August 30, 2012

Last Update Submit

February 21, 2018

Conditions

Keywords

nulliparousIUDIUSinsertionexpulsion

Outcome Measures

Primary Outcomes (1)

  • The effect of uterine size or posture on IUD insertion.

    The size of the uterine cavity (cm) and the flexion angle of the uterus are determined at insertion using ultrasonography. This is compared with assessment of perception of insertion pain both by the patient and the inserting doctor is evaluated as well as the easiness if insertion (by the doctor).

    Day 1

Secondary Outcomes (2)

  • Satisfaction and continuation rate with intrauterine contraception.

    3 months

  • Satisfaction and continuation rate with intrauterine contraception.

    12 months

Study Arms (2)

LNG-IUS

Nulliparous women

Other: Evaluation of uterine size and posture with ultrasound, IUD insertion, one year follow-up.

Cu-IUD

Nulliparous women

Other: Evaluation of uterine size and posture with ultrasound, IUD insertion, one year follow-up.

Interventions

Evaluation of uterine size and posture with ultrasound, IUD insertion, one year follow-up.

Cu-IUDLNG-IUS

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

The study population consists of nulliparous women attending the centralized Family planning center of the City of Helsinki requesting intrauterine contraception, either the LNG-IUS or a Cu-IUD.

You may qualify if:

  • \- nulliparous women with no previous history of IUD use

You may not qualify if:

  • malformation of uterus
  • myomas
  • acute gynecological infection
  • malignant uterine or cervical tumor
  • In addition if requesting a Cu-IUD
  • heavy menstruations
  • iron deficiency
  • bleeding disorder
  • copper allergy or Wilson's disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Contraceptive unit of city of Helsinki

Helsinki, Finland

Location

Related Publications (2)

  • Kaislasuo J, Heikinheimo O, Lahteenmaki P, Suhonen S. Menstrual characteristics and ultrasonographic uterine cavity measurements predict bleeding and pain in nulligravid women using intrauterine contraception. Hum Reprod. 2015 Jul;30(7):1580-8. doi: 10.1093/humrep/dev102. Epub 2015 May 19.

  • Kaislasuo J, Heikinheimo O, Lahteenmaki P, Suhonen S. Predicting painful or difficult intrauterine device insertion in nulligravid women. Obstet Gynecol. 2014 Aug;124(2 Pt 1):345-353. doi: 10.1097/AOG.0000000000000362.

MeSH Terms

Interventions

PostureHigh-Energy Shock Waves

Intervention Hierarchy (Ancestors)

Musculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaUltrasonic WavesSoundRadiation, NonionizingRadiationPhysical Phenomena

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physician in chief, Centralized Family Planning, City of Helsinki Health Centre

Study Record Dates

First Submitted

August 30, 2012

First Posted

September 14, 2012

Study Start

January 1, 2011

Primary Completion

July 1, 2013

Study Completion

July 1, 2013

Last Updated

February 23, 2018

Record last verified: 2018-02

Locations