NCT01681901

Brief Summary

This pilot clinical trial studies ultrasound in detecting lymph node metastasis in older patients with undergoing breast sonography. Diagnostic procedures, such as ultrasound, may help find breast cancer and find out how far the disease has spread

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jun 2006

Shorter than P25 for all trials

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 7, 2006

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2007

Completed
5.4 years until next milestone

First Submitted

Initial submission to the registry

September 5, 2012

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 10, 2012

Completed
Last Updated

April 13, 2017

Status Verified

April 1, 2017

Enrollment Period

10 months

First QC Date

September 5, 2012

Last Update Submit

April 12, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Proportion of successful evaluations, defined as the consistent capture of the data for geometry, morphology, qualitative vascular information, and quantitative vascular information on 3 axillary lymph nodes

    The proposed methodology will be considered unfeasible if the proportion of successful evaluations is =\< 0.7.

    at 15 minutes following breast sonogram

Secondary Outcomes (4)

  • Accuracy of lymph node geometry, measured with a longitudinal and transverse ratio, to determine guidelines for characterizing micro metastases to the lymph nodes

    3 months

  • Accuracy of lymph node morphology, assessed for shape and echogenicity, to determine guidelines for characterizing micro metastases to the lymph nodes

    3 months

  • Accuracy of lymph node vascularity, assessed with color doppler, to determine guidelines for characterizing micro metastases to the lymph nodes

    3 months

  • Accuracy of lymphatic flow, measured with spectral doppler, to determine guidelines for characterizing micro metastases to the lymph nodes

    3 months

Study Arms (1)

Diagnostic (ultrasound)

Patients undergo breast ultrasound imaging.

Procedure: ultrasound imaging

Interventions

Undergo ultrasound

Also known as: ultrasonography, ultrasound, ultrasound test
Diagnostic (ultrasound)

Eligibility Criteria

Age55 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Inclusion Criteria: * Patients referred for a breast ultrasound * Patients who have had a mammogram with a Breast Imaging Reporting and Data System (BIRADS) of \>= 4 * Patients who are undiagnosed for breast cancer

You may qualify if:

  • Patients referred for a breast ultrasound
  • Patients who have had a mammogram with a Breast Imaging Reporting and Data System (BIRADS) of \>= 4
  • Patients who are undiagnosed for breast cancer

You may not qualify if:

  • Patients who have had breast cancer surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

MeSH Terms

Conditions

Breast Neoplasms

Interventions

High-Energy Shock Waves

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Ultrasonic WavesSoundRadiation, NonionizingRadiationPhysical Phenomena

Study Officials

  • Kevin Evans

    Ohio State University Comprehensive Cancer Center

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 5, 2012

First Posted

September 10, 2012

Study Start

June 7, 2006

Primary Completion

April 1, 2007

Study Completion

April 1, 2007

Last Updated

April 13, 2017

Record last verified: 2017-04