Evaluation of Brain MRI and Clinical Characteristics of Adolescents With Bipolar Disorder and Children of Parents With Bipolar Disorder
1 other identifier
observational
60
1 country
1
Brief Summary
Genetic transition is important in the etiology of bipolar disorder (BD). So, evaluation of children of BD parents and diagnosed with and BD children whether or not brain has affected zones. These groups were compared to healthy controls and whether or not the mental health of children is influenced will be evaluated by the clinical investigation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jul 2011
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2011
CompletedFirst Submitted
Initial submission to the registry
August 31, 2012
CompletedFirst Posted
Study publicly available on registry
September 5, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2013
CompletedSeptember 5, 2012
August 1, 2012
1.9 years
August 31, 2012
September 4, 2012
Conditions
Keywords
Study Arms (3)
Patient group
Children with BD, (20 children) 12-18 year-old who agreed to participate in the study will be established.
Risk group
Twenty healthy children of 12-18 years old who have mothers and/or fathers who previously assessed by an adult psychiatrist and diagnosed as BD according to DSM-IV diagnostic criteria, and who agreed to participate in the study. The age and gender of the groups will be matched.
Healthy control group
Twenty participants between the ages of 12-18 who agree to participate in the study and whose family members do not have BD. The age and the gender of the groups will be matched.
Eligibility Criteria
In this study, the cranial MRI findings and clinical features in adolescents with bipolar disorder and the same age and sex matched children who have parents with BD and healthy controls were investigated.
You may qualify if:
- Children with BD between the ages of 12-18
- Parents with BD who have children between the ages of 12-18
- Healthy children whose parents do not have BD
- Patients who does not have mental or organic disability to answer the questions
- Graduated from primary school
You may not qualify if:
- Patients who have mental or organic disability to answer the questions
- Patients who have a history of any chronic disease which is likely to affect the central nervous system
- Patients who have a contraindication for any first application for Magnetic Resonance Imaging (MRI)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ondokuz Mayis University Medical Faculty Department of Child and Adolescent Psychiatry
Samsun, 55139, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
August 31, 2012
First Posted
September 5, 2012
Study Start
July 1, 2011
Primary Completion
June 1, 2013
Study Completion
June 1, 2013
Last Updated
September 5, 2012
Record last verified: 2012-08