Perifollicular Doppler in Natural Cycle In Vitro Fertilization

NCT01668212 | Completed

• 1 other identifier: OVO-11-01
• Study Type: observational
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

Perifollicular Doppler could reflect the quality of the follicle's vascularization and, consequently, the one of the oocyte that ensues from it. Perifollicuar Doppler is the analysis, in ultrasound, of the blood flow in vessels surrounding the follicle. The goal of this study is to evaluate if there is a link, in natural cycle In Vitro Fertilization, between the quality of the vascularization and the one of the oocyte, the embryo and the pregnancy.

Conditions

Infertility

Outcome Measures

Primary Outcomes (1)

• Quality perifollicular doppler and quality of the oocyte

  The measurements are done twice; on days of induction and oocyte retrieval. During the blood sample collection on the day of the induction, there is also a measurement of progesterone, estradiol and luteinizing hormone (LH).

  2 weeks

Study Arms (1)

natural In Vitro Fertilization cycle

Patient doing following natural In Vitro fertilization cycle

Procedure: Doppler ultrasound

Interventions

Doppler ultrasound PROCEDURE

Doppler Ultrasound

natural In Vitro Fertilization cycle

Eligibility Criteria

• Age: 18 Years - 38 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Women following In Vitro Fertilization cycle

You may qualify if:

• Patient with a natural In Vitro Fertilization cycle.
• Patient under 38 years old
• Body mass indice under 35
• Ovulatory cycles between 20-35 days

You may not qualify if:

• Patient with a stimulation In Vitro Fertilization cycle
• Patient with a naturalIn Vitro Fertilization cycle with egg donor
• Patient with a natural In Vitro Fertilization cycle with freezing embryo
• Smoking patient
• Diabetic patient
• Patient with treatment of antihypertensive drug, anticoagulant, antiplatelet, vasodilator
• Body mass indice over 35
• Patient over 38 years old
• Patient without ovulation or cycle over 35 days
• Percutaneous Epididymal Sperm Aspiration (PESA), Testicular Sperm Extraction (TESE) or micro TESE

Sponsors & Collaborators

• Clinique Ovo: lead

Study Sites (1)

Ovo Fertilité

Montreal, Quebec, H4P 2S4, Canada

Location

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital Diseases; Urogenital Diseases

Study Officials

• Delphine Delrieu, MD

  Clinique Ovo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 19, 2012
• First Posted: August 20, 2012
• Study Start: March 1, 2012
• Primary Completion: May 1, 2013
• Last Updated: June 24, 2013

Record last verified: 2013-06

Locations

CA (1)