NCT01667887

Brief Summary

The objective of this study is to document callus formation and healing of fractures stabilized with locking plates utilizing modern MotionLoc screws that provide controlled axial micro-motion to actively promote fracture healing.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
33

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2011

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2012

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 15, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 17, 2012

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2013

Completed
Last Updated

January 29, 2013

Status Verified

January 1, 2013

Enrollment Period

1.1 years

First QC Date

August 15, 2012

Last Update Submit

January 28, 2013

Conditions

Keywords

Far Cortical LockingDistal Femur FractureLocking PlateMotionLocFracture Fixation

Outcome Measures

Primary Outcomes (1)

  • Fracture Healing

    Fracture healing is defined clinically by the ability of pain-free weight bearing, and radiographically by callus formation and bridging.

    6, 12, and 24 weeks post surgery

Secondary Outcomes (4)

  • Periosteal Callus Size

    6, 12, 24 weeks post surgery

  • Bridging Callus from CT

    12 weeks post surgery

  • Fixation Failure

    24 weeks post surgery

  • Hardware failure

    6, 12, 24 weeks post surgery

Study Arms (1)

Femur Fractures

Patients with Distal Femur Fractures

Eligibility Criteria

Age17 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Distal femur fractures (AO/OTA Type 33A and 33C)

You may qualify if:

  • Patients with distal femur fracture (AO/OTA Type 33A and 33C)
  • Patients 17 years of age and over.
  • Patients able to be operated on by selected surgeons at the participating centers.

You may not qualify if:

  • Pregnancy
  • Patients who are enrolled in an investigational treatment trial.
  • Patients who are not expected to survive the follow-up period.
  • Considered an inappropriate participant by the study physician.
  • Revision surgery
  • Patients currently incarcerated or awaiting incarceration.
  • Severe spinal injury with neurological deficit resulting in paralysis.
  • Fracture fixed more then 28 days after injury.
  • Acute or chronic local or systemic infections
  • Periprosthetic fractures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Legacy Health System

Portland, Oregon, 97232, United States

Location

Related Links

MeSH Terms

Conditions

Femoral Fractures, Distal

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesLeg Injuries

Study Officials

  • Michael Bottlang, PhD

    Legacy Biomechanics Laboratory

    PRINCIPAL INVESTIGATOR
  • Steven Madey, MD

    Legacy Health System

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director, Legacy Biomechanics Laboratory

Study Record Dates

First Submitted

August 15, 2012

First Posted

August 17, 2012

Study Start

April 1, 2011

Primary Completion

May 1, 2012

Study Completion

January 1, 2013

Last Updated

January 29, 2013

Record last verified: 2013-01

Locations