NCT01667835

Brief Summary

The purpose of this randomized, control pilot study is to measure the effects of a gentle, 12 week hatha yoga program on post-menopausal, obese, sedentary South Asian women at risk for cardiovascular disease. Hatha yoga is a form of structured physical exercises known as asanas, combined with breathing exercises called pranayama, and relaxation techniques. The yoga intervention consists of 9 different yoga poses (asanas) and 3 different breathing exercises (pranayama) that can be easily replicated and readily performed by individuals who are middle-aged and older, overweight, unfit, or who suffer from a chronic illness.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P50-P75 for phase_1

Timeline
Completed

Started Nov 2012

Typical duration for phase_1

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 17, 2012

Completed
2 months until next milestone

First Posted

Study publicly available on registry

August 17, 2012

Completed
3 months until next milestone

Study Start

First participant enrolled

November 1, 2012

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2015

Completed
Last Updated

November 19, 2012

Status Verified

November 1, 2012

Enrollment Period

2.1 years

First QC Date

June 17, 2012

Last Update Submit

November 16, 2012

Conditions

Keywords

yogapostmenopausal, sedentary South Asian women

Outcome Measures

Primary Outcomes (1)

  • Change in blood pressure

    blood pressure is measured as a specific physiologic index of cardiovascular risk.

    baseline, at end of study (12 wks), & 3 months post-study

Secondary Outcomes (13)

  • Change in subjective well-being

    baseline, at end of study (12 wks), & 3 months post-study

  • Change in perceived physical well-being

    baseline, end of study (12 wks) & 3 months post-study

  • Change in insulin sensitivity

    baseline, end of study (12 wks) & 3 months post-study

  • Change in inflammation

    baseline, end of study (12 wks) & 3 months post-study

  • Change in serum total cholesterol

    baseline, end of study (12 wks) & 3 months post-study

  • +8 more secondary outcomes

Study Arms (2)

Yoga Intervention

EXPERIMENTAL
Behavioral: Yoga Intervention

Control

NO INTERVENTION

Interventions

12 week 90 minute hatha yoga session offered three (3x) per week. Hatha yoga is a form of structured physical exercises known as asanas, combined with breathing exercises called pranayama, and relaxation techniques. The yoga intervention consists of 9 different yoga poses (asanas) and 3 different breathing exercises (pranayama) that can be easily replicated and readily performed by individuals who are middle-aged and older, overweight, unfit, or who suffer from a chronic illness.

Yoga Intervention

Eligibility Criteria

Age40 Years - 65 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years old
  • Postmenopausal (amenorrhea for ≥ 12 months)
  • Overweight as evidenced by a body mass index (BMI) ≥ 25 kg/m2), or waist circumference ≥ 80 cm, or have a first degree relative with diabetes or essential hypertension
  • Sedentary, do not do a regular exercise program (exercising for 20 minutes at sufficient intensity to produce sweating less than 2x/week)
  • Self-identify as a South Asian (sometimes referred to as East Indian in Canada and may be defined "as any person who reports an ethnicity associated with the southern part of Asia or who self-identifies as part of the South Asian visible minority group. This definition encompasses people from a great diversity of ethnic backgrounds, including those with Bangladeshi, Bengali, East Indian, Goan, Gujarati, Hindu, Ismaili, Kashmiri, Nepali, Pakistani, Punjabi, Sikh, Sinhalese, South Asian, Sri Lankan and Tamil ancestry. South Asians may have been born in Canada, on the Indian sub-continent, in the Caribbean, in Africa, in Great Britain or elsewhere
  • Given consent to research protocol and willingness to be randomized to either the treatment (yoga) or control (no yoga) group.

You may not qualify if:

  • Have had a period within the last year
  • Are not between the ages of 40 and 65
  • Have experience with yoga within the last 12 months
  • Have any serious disease or condition such as diabetes, serious high blood pressure or heart problems, kidney disease, severe asthma, cancer (except for skin cancer that is not melanoma)
  • Have a major brain or nervous system diagnosis, such as Parkinson's disease or stroke
  • Have a severe infectious or other medical illness right now such as pneumonia
  • Use medications to lower blood sugar levels
  • Have serious back, hip, or neck problems or pain in joints or bones that would prevent the safe completion of a gentle 12 week Hatha yoga program
  • Regularly use an assistive device (e.g., cane, walker) to walk

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

The Jim Pattison Outpatient Care and Surgery Services, Cardiovascular Outpatient Clinic

Surrey, British Columbia, V3T 0G9, Canada

RECRUITING

Kwantlen Polytechnic University

Surrey, British Columbia, V3W 2M8, Canada

NOT YET RECRUITING

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

  • Amandah L Hoogbruin, PhD

    Kwantlen Polytechnic University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Amandah L Hoogbruin, PhD

CONTACT

Raymond Dong, FRCPC

CONTACT

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Community & Health Studies Faculty member

Study Record Dates

First Submitted

June 17, 2012

First Posted

August 17, 2012

Study Start

November 1, 2012

Primary Completion

December 1, 2014

Study Completion

August 1, 2015

Last Updated

November 19, 2012

Record last verified: 2012-11

Locations