Study on the Effect of Electroacupuncture at Both Zusanli and at Both Yanglingquan Acupoints on Cardiovascular Activity

NCT01665105 | Completed

• 1 other identifier: DMR101-IRB2-101
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this present study was to investigate the effect of electroacupuncture at both Zusanli and at both Yanglingquan acupoints on autonomic nerve modulating cardiovascular activity, and skin blood flow and skin temperature. The investigators use pulse rate variability to investigate autonomic nerve modulates cardiovascular function, and using distant skin blood flow and skin temperature recordings to investigate the relationship between the same names meridian of hand and foot.

Conditions

Reaction of Autonomic Nervous System; Reaction of Acupuncture; Reaction of Blood Circulation

Keywords

Pulse Rate Variability; Skin Blood Flow; Skin Temperature; Electroacupuncture; Zusanli; Yanglingquan

Outcome Measures

Primary Outcomes (1)

• From pulse wave, pulse rate variability and skin blood flow to measure cardiovascular activities with electroacupuncture at Zusanli and at Yanglingquan.

  Each session was divided into three periods of before electroacupuncture, electroacupuncture, and post electroacupuncture. Each period was 20 min in duration. During each period, the final 5 min of the period was pulse rate variability recordings of left hand by ANSWatch(TS-0411 model). This data were storage as primary outcomes and analyzed in a personal computer.

  each period was 20 min in duration. The parameters of pulse wave, 5-min pulse rate variability were recorded at the end of each period.

Secondary Outcomes (1)

• From skin blood flow and skin temperature to measure cardiovascular activities with electroacupuncture at Zusanli and at Yanglingquan.

  each period was 20 min in duration. The parameters of skin blood flow and skin temperature were recorded at the end of each period.

Study Arms (3)

Zusanli Group

EXPERIMENTAL

electroacupuncture at both Zusanli on the leg, and record simultaneously the pulse rate variability as well as take the skin blood flow and skin temperature recordings at Hoku's and Zhongzhu's region of right hand.

Device: acupuncture

Yanlingquan Group

ACTIVE COMPARATOR

electroacupuncture at both Yanglingquan on the leg, and record simultaneously the pulse rate variability as well as take the skin blood flow and skin temperature recordings at Hoku's and Zhongzhu's region of right hand.

Device: acupuncture

Sham Group

SHAM COMPARATOR

acupuncture without electrical stimulation at non-acupoint on the leg, and record simultaneously pulse rate variability as well as take the skin blood flow and skin temperature recordings at Hoku's and Zhongzhu's region of right hand.

Device: acupuncture

Interventions

acupuncture DEVICE

electroacupuncture at at Zusanli, electroacupuncture at Yanglingquan, and acupuncture at non-acupoint.

Sham Group; Yanlingquan Group; Zusanli Group

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• healthy volunteers without without cardiac disease, taking medications, smoking
• before experiment, abstaining from caffeine, alcohol for 8 hours.
• age between 20-40.

You may not qualify if:

• volunteers with cardiac disease, taking medications, smoking
• age greater than 40 or less than 20.

Sponsors & Collaborators

• China Medical University Hospital: lead

Study Sites (1)

China Medical University Hospital

Taichung, 40447, Taiwan

Location

MeSH Terms

Interventions

Acupuncture Therapy

Intervention Hierarchy (Ancestors)

Complementary Therapies; Therapeutics

Study Officials

• Ching-Liang Hsieh, professor

  China Medical University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 20, 2012
• First Posted: August 15, 2012
• Study Start: July 1, 2012
• Primary Completion: November 1, 2012
• Study Completion: May 1, 2013
• Last Updated: July 12, 2013

Record last verified: 2013-07

Locations

TW (1)